Strategies for functionalizing diverse tetrahedral framework nucleic acids (tFNAs) have been
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …

The physicochemical nature of DNA allows the assembly of highly predictable structures via
several fabrication strategies, which have been applied to make breakthroughs in various …

Rapid and efficient tools for early cancer detection have diagnostic and therapeutic value.
Given that the DNA hairpin‐based hybridization chain reaction (HCR) is effective in …

Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

Catalytic hairpin assembly (CHA) with advantages of high efficiency, flexible design, and
mild reaction condition is considered a promising molecular amplifier. Modified working …

CRISPR diagnostics (CRISPR-Dx) offer a wide range of enhancements compared to
traditional nanobiosensors by taking advantage of the excellent trans-cleavage activity of the …

In recent years, DNA has been widely noted as a kind of material that can be used to
construct building blocks for biosensing, in vivo imaging, drug development, and disease …

Nucleic acid amplification techniques have always been one of the hot spots of research,
especially in the outbreak of COVID-19. From the initial polymerase chain reaction (PCR) to …

Over the past few decades, DNA nanotechnology engenders a vast variety of programmable
nanostructures utilizing Watson–Crick base pairing. Due to their precise engineering …