[HTML][HTML] Adipose tissue and insulin resistance in obese

B Ahmed, R Sultana, MW Greene - Biomedicine & Pharmacotherapy, 2021‏ - Elsevier
Currently, obesity has become a global health issue and is referred to as an epidemic.
Dysfunctional obese adipose tissue plays a pivotal role in the development of insulin …

[HTML][HTML] Negative effects of a high-fat diet on intestinal permeability: a review

MW Rohr, CA Narasimhulu, TA Rudeski-Rohr… - Advances in …, 2020‏ - Elsevier
The intestinal tract is the largest barrier between a person and the environment. In this role,
the intestinal tract is responsible not only for absorbing essential dietary nutrients, but also …

The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

K Kazankov, SMD Jørgensen, KL Thomsen… - Nature reviews …, 2019‏ - nature.com
Nonalcoholic fatty liver disease (NAFLD) and its inflammatory and often progressive subtype
nonalcoholic steatohepatitis (NASH) are becoming the leading cause of liver-related …

The effect of palmitic acid on inflammatory response in macrophages: an overview of molecular mechanisms

J Korbecki, K Bajdak-Rusinek - Inflammation Research, 2019‏ - Springer
Palmitic acid is a saturated fatty acid whose blood concentration is elevated in obese
patients. This causes inflammatory responses, where toll-like receptors (TLR), TLR2 and …

Omega-3 versus omega-6 polyunsaturated fatty acids in the prevention and treatment of inflammatory skin diseases

A Balić, D Vlašić, K Žužul, B Marinović… - International journal of …, 2020‏ - mdpi.com
Omega-3 (ω-3) and omega-6 (ω-6) polyunsaturated fatty acids (PUFAs) are nowadays
desirable components of oils with special dietary and functional properties. Their therapeutic …

Obesity, inflammation, toll-like receptor 4 and fatty acids

MM Rogero, PC Calder - Nutrients, 2018‏ - mdpi.com
Obesity leads to an inflammatory condition that is directly involved in the etiology of
cardiovascular diseases, type 2 diabetes mellitus, and certain types of cancer. The classic …

Inflammaging and 'Garb-aging'

C Franceschi, P Garagnani, G Vitale, M Capri… - Trends in Endocrinology …, 2017‏ - cell.com
'Inflammaging'refers to the chronic, low-grade inflammation that characterizes aging.
Inflammaging is macrophage centered, involves several tissues and organs, including the …

[HTML][HTML] Common neurodegenerative pathways in obesity, diabetes, and Alzheimer's disease

S Pugazhenthi, L Qin, PH Reddy - … acta (BBA)-molecular basis of disease, 2017‏ - Elsevier
Cognitive decline in chronic diabetic patients is a less investigated topic. Diabetes and
obesity are among the modifiable risk factors for Alzheimer's disease (AD), the most …

Foundations of immunometabolism and implications for metabolic health and disease

GS Hotamisligil - Immunity, 2017‏ - cell.com
Highly ordered interactions between immune and metabolic responses are evolutionarily
conserved and paramount for tissue and organismal health. Disruption of these interactions …

[HTML][HTML] Acne, microbiome, and probiotics: The gut–skin axis

P Sánchez-Pellicer, L Navarro-Moratalla… - Microorganisms, 2022‏ - mdpi.com
The objective of this narrative review was to check the influence of the human microbiota in
the pathogenesis of acne and how the treatment with probiotics as adjuvant or alternative …