Oxidation–reduction (redox) reactions are central to the existence of life. Reactive species of
oxygen, nitrogen and sulfur mediate redox control of a wide range of essential cellular …

Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …

In the open metabolic system, redox-related signaling requires continuous monitoring and
fine-tuning of the steady-state redox set point. The ongoing oxidative metabolism is a …

Hydrogen peroxide emerged as major redox metabolite operative in redox sensing,
signaling and redox regulation. Generation, transport and capture of H 2 O 2 in biological …

Abstract “Oxidative stress” as a concept in redox biology and medicine has been formulated
in 1985; at the beginning of 2015, approx. 138,000 PubMed entries show for this term. This …

Utilization of molecular oxygen by aerobic organisms inevitably results in the formation of a
number of oxygen-containing reactive species that are collectively known as reactive …

Cysteine is one of the least abundant amino acids, yet it is frequently found as a highly
conserved residue within functional (regulatory, catalytic, or binding) sites in proteins. It is …

Significance: The redox code is a set of principles that defines the positioning of the
nicotinamide adenine dinucleotide (NAD, NADP) and thiol/disulfide and other redox systems …

Hydrogen peroxide, the nonradical 2-electron reduction product of oxygen, is a normal
aerobic metabolite occurring at about 10 nm intracellular concentration. In liver, it is …

Many pathological conditions are predominantly associated with oxidative stress, arising
from reactive oxygen species (ROS); therefore, the modulation of redox activities has been a …