Metabolic engineers endeavor to create a bio-based manufacturing industry using microbes
to produce fuels, chemicals, and medicines. Plant natural products (PNPs) are historically …

Metabolic engineering is the science of rewiring the metabolism of cells to enhance
production of native metabolites or to endow cells with the ability to produce new products …

Advances in synthetic biology enable microbial hosts to synthesize valuable natural
products in an efficient, cost-competitive and safe manner. However, current engineering …

The production of bioactive plant compounds using microbial hosts is considered a safe,
cost-competitive and scalable approach to their production. However, microbial production …

For thousands of years, the yeast Saccharomyces cerevisiae (S. cerevisiae) has served as a
cell factory for the production of bread, beer, and wine. In more recent years, this yeast has …

In this study, 4 Lactobacillus plantarum strains and 5 Lactobacillus fermentum strains
adapting well to the unfavorable fruit system were isolated under different fruit environments …

The flavonoid xanthohumol is an important flavor substance in the brewing industry that has
a wide variety of bioactivities. However, its unstable structure results in its low content in …

The aromatic nature of shikimate pathway intermediates gives rise to a wealth of potential
bio-replacements for commonly fossil fuel-derived aromatics, as well as naturally produced …

Polyketides are a diverse class of molecules sought after for their valuable properties,
including as potential pharmaceuticals. Previously, we demonstrated that the oleaginous …

Resveratrol is a natural antioxidant compound, used as food supplement and cosmetic
ingredient. Microbial production of resveratrol has until now been achieved by …