The role of oxidative stress in atherosclerosis

M Batty, MR Bennett, E Yu - Cells, 2022 - mdpi.com
Atherosclerosis is a chronic inflammatory disease of the vascular system and is the leading
cause of cardiovascular diseases worldwide. Excessive generation of reactive oxygen …

Effect of ginger on inflammatory diseases

P Ballester, B Cerdá, R Arcusa, J Marhuenda… - Molecules, 2022 - mdpi.com
Ulcerative colitis, Crohn's disease, rheumatoid arthritis, psoriasis, and lupus erythematosus
are some of common inflammatory diseases. These affections are highly disabling and …

Viral hepatitis, cholesterol metabolism, and cholesterol-lowering natural compounds

JW Liou, H Mani, JH Yen - International Journal of Molecular Sciences, 2022 - mdpi.com
Hepatitis is defined as inflammation of the liver; it can be acute or chronic. In chronic cases,
the prolonged inflammation gradually damages the liver, resulting in liver fibrosis, cirrhosis …

Bioactive Triterpenes of Protium heptaphyllum Gum Resin Extract Display Cholesterol-Lowering Potential

G Mannino, P Iovino, A Lauria, T Genova… - International Journal of …, 2021 - mdpi.com
Hypercholesterolemia is one of the major causes of cardiovascular disease, the risk of which
is further increased if other forms of dyslipidemia occur. Current therapeutic strategies …

In Silico Study of Alkaloids: Neferine and Berbamine Potentially Inhibit the SARS‐CoV‐2 RNA‐Dependent RNA Polymerase

R Marahatha, A Shrestha, K Sharma… - Journal of …, 2022 - Wiley Online Library
The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus that causes
COVID‐19, has been a global concern. While there have been some vaccines and drugs …

Understanding hypocholesterolemic activity of soy isoflavones: Completing the puzzle through computational simulations

FE Hermanto, W Warsito, M Rifa'i… - Journal of Biomolecular …, 2023 - Taylor & Francis
The hypocholesterolemic activity of soy isoflavones has been studied, but the exact
mechanism underlying the activity remains unclear. This study reveals the proposed …

Repositioning of HMG-CoA reductase inhibitors as adjuvants in the modulation of efflux pump-mediated bacterial and tumor resistance

Z Schelz, HF Muddather, I Zupkó - Antibiotics, 2023 - mdpi.com
Efflux pump (EP)-mediated multidrug resistance (MDR) seems ubiquitous in bacterial
infections and neoplastic diseases. The diversity and lack of specificity of these efflux …

N-acetylcysteine and zinc sulphate abate di-2-ethylhexyl phthalate-mediated reproductive dysfunction in rats: Focus on oxidative and sex hormone receptors …

VO Emojevwe, MO Oyovwi, KE Adewole… - Asian Pacific Journal …, 2024 - journals.lww.com
Objective: To investigate the potential of N-acetylcysteine (NAC) and zinc sulphate (ZnSO 4)
in mitigating reproductive dysfunction caused by di-2-ethylhexyl phthalate (DEHP) in rats …

[HTML][HTML] The effects of L-carnitine-loaded solid lipid nanoparticles on performance, antioxidant parameters, and expression of genes associated with cholesterol …

M Eskandani, B Navidshad, M Eskandani… - Poultry Science, 2022 - Elsevier
The purpose of this study was to investigate the production performance, antioxidant
parameters, egg yolk cholesterol content, and expression of genes related to cholesterol …

In vitro and in silico studies for the identification of potent metabolites of some high-altitude medicinal plants from Nepal inhibiting SARS-CoV-2 spike protein

S Basnet, R Marahatha, A Shrestha, S Bhattarai… - Molecules, 2022 - mdpi.com
Despite ongoing vaccination programs against COVID-19 around the world, cases of
infection are still rising with new variants. This infers that an effective antiviral drug against …