The presence and biological importance of DNA secondary structures in eukaryotic
promoters are becoming increasingly recognized among chemists and biologists as …

Chiral materials related to circularly polarized luminescence (CPL) make up a rapidly
develo** new field that has broad application prospects in optoelectronic devices …

A series of luminescent iridium (III) complexes were synthesised and evaluated for their
ability to act as luminescent G-quadruplex-selective probes. The iridium (III) complex 9 [Ir …

Both human telomeric G-rich and C-rich DNA have been considered as specific drug targets
for cancer therapy. However, due to i-motif structure instability and lack of specific binding …

G-quadruplexes are unusual DNA and RNA secondary structures ubiquitous in a variety of
organisms including vertebrates, plants, viruses and bacteria. The folding topology and …

DNA in command: An enantioselective Diels–Alder reaction can be achieved using human
telomeric G‐quadruplex DNA‐based catalysts. The absolute configuration of the product can …

DNA has been a key target for cancer therapy, with a range of compounds able to bind and
either impair its processing or induce damage. Targeting DNA with small molecules in a truly …

Telomerase is over‐expressed in over 85% of all known human tumors. This renders the
enzyme a valuable biomarker for cancer diagnosis and an important therapeutic target. The …

Long human telomeric fragments can form stable, higher-order G-quadruplex structures,
recently identified in human cells, which are potential drug targets. However, there are very …

Three water-soluble ruthenium (II) complexes with chiral 4-(2, 3-dihydroxypropyl)-formamide
oxoaporphine (FOA) were synthesized and characterized. It was found that these ruthenium …