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Extracellular miRNAs: from biomarkers to mediators of physiology and disease
miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
miRNAs role in bladder cancer pathogenesis and targeted therapy: signaling pathways interplay–a review
Bladder cancer (BC) is the 11th most popular cancer in females and 4th in males. A lot of
efforts have been exerted to improve BC patients' care. Besides, new approaches have …
efforts have been exerted to improve BC patients' care. Besides, new approaches have …
miRNAs as cornerstones in chronic lymphocytic leukemia pathogenesis and therapeutic resistance–an emphasis on the interaction of signaling pathways
Chronic lymphocytic leukemia (CLL) accounts for the vast majority of cases of leukemia.
Patients of advanced age are more likely to develop the condition, which has a highly varied …
Patients of advanced age are more likely to develop the condition, which has a highly varied …
Preservation and storage stability of extracellular vesicles for therapeutic applications
Abstract Recently, extracellular vesicles (EVs)—including exosomes, microvesicles, and
others—have attracted interest as cell-derived biotherapeutics and drug delivery vehicles for …
others—have attracted interest as cell-derived biotherapeutics and drug delivery vehicles for …
Significance of miRNAs on the thyroid cancer progression and resistance to treatment with special attention to the role of cross-talk between signaling pathways
Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. It has many types, the
Papillary thyroid cancer (PTC)(most common and follicular thyroid carcinoma (FTC). Several …
Papillary thyroid cancer (PTC)(most common and follicular thyroid carcinoma (FTC). Several …
Circulating miRNA analysis for cancer diagnostics and therapy
Successful treatment of cancer depends on early diagnosis and effective monitoring of
patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity …
patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity …
Epilepsy biomarkers–toward etiology and pathology specificity
A biomarker is a characteristic that is measured as an indicator of normal biologic
processes, pathogenic processes, or responses to an exposure or intervention, including …
processes, pathogenic processes, or responses to an exposure or intervention, including …
The procurement, storage, and quality assurance of frozen blood and tissue biospecimens in pathology, biorepository, and biobank settings
Well preserved frozen biospecimens are ideal for evaluating the genome, transcriptome,
and proteome. While papers reviewing individual aspects of frozen biospecimens are …
and proteome. While papers reviewing individual aspects of frozen biospecimens are …
Challenges in using circulating miRNAs as cancer biomarkers
P Tiberio, M Callari, V Angeloni… - BioMed research …, 2015 - Wiley Online Library
In the last years, circulating miRNAs have emerged as a new class of promising cancer
biomarkers. Independent studies have shown the feasibility of using these small RNAs as …
biomarkers. Independent studies have shown the feasibility of using these small RNAs as …
Mechanisms and biomarkers of cancer-associated thrombosis
Cancer-associated thrombosis is a leading cause of non-cancer death in cancer patients
and is comprised of both arterial and venous thromboembolism (VTE). There are multiple …
and is comprised of both arterial and venous thromboembolism (VTE). There are multiple …