Why is placentation abnormal in preeclampsia?
SJ Fisher - American journal of obstetrics and gynecology, 2015 - Elsevier
The causes of preeclampsia remain one of the great medical mysteries of our time. This
syndrome is thought to occur in 2 stages with abnormal placentation leading to a maternal …
syndrome is thought to occur in 2 stages with abnormal placentation leading to a maternal …
Pre-eclampsia part 1: current understanding of its pathophysiology
Pre-eclampsia is characterized by new-onset hypertension and proteinuria at≥ 20 weeks of
gestation. In the absence of proteinuria, hypertension together with evidence of systemic …
gestation. In the absence of proteinuria, hypertension together with evidence of systemic …
Preeclampsia, a disease of the maternal endothelium: the role of antiangiogenic factors and implications for later cardiovascular disease
Preeclampsia is a clinical syndrome defined as the new onset of hypertension and
proteinuria during the second half of pregnancy. 1 It afflicts 3% to 5% of pregnancies and is …
proteinuria during the second half of pregnancy. 1 It afflicts 3% to 5% of pregnancies and is …
Metformin, the aspirin of the 21st century: its role in gestational diabetes mellitus, prevention of preeclampsia and cancer, and the promotion of longevity
Metformin is everywhere. Originally introduced in clinical practice as an antidiabetic agent,
its role as a therapeutic agent is expanding to include treatment of prediabetes mellitus …
its role as a therapeutic agent is expanding to include treatment of prediabetes mellitus …
Endothelial cells in physiology and in the pathophysiology of vascular disorders
DB Cines, ES Pollak, CA Buck… - Blood, The Journal …, 1998 - ashpublications.org
PART I THE ENDOTHELIUM has long been viewed as an inert cellophane-like membrane
that lines the circulatory system with its primary essential function being the maintenance of …
that lines the circulatory system with its primary essential function being the maintenance of …
Preeclampsia: an endothelial cell disorder
Despite intense study preeclampsia remains enigmatic and a major cause of maternal and
fetal morbidity and mortality. Most investigative efforts have focused on the hypertensive …
fetal morbidity and mortality. Most investigative efforts have focused on the hypertensive …
Genetic conflicts in human pregnancy
D Haig - The Quarterly review of biology, 1993 - journals.uchicago.edu
Pragnancy has commonly been viewed as a cooperative interaction between a mother and
her fetus. The effects of natural selection on genes expressed in fetuses, however, may be …
her fetus. The effects of natural selection on genes expressed in fetuses, however, may be …
Pathogenesis of preeclampsia
BC Young, RJ Levine… - Annual Review of …, 2010 - annualreviews.org
Preeclampsia is a systemic syndrome that occurs in 3 to 5% of pregnant women and
classically manifests as new-onset hypertension and proteinuria after 20 weeks of gestation …
classically manifests as new-onset hypertension and proteinuria after 20 weeks of gestation …
From pregnancy to preeclampsia: a key role for estrogens
Preeclampsia (PE) results in placental dysfunction and is one of the primary causes of
maternal and fetal mortality and morbidity. During pregnancy, estrogen is produced primarily …
maternal and fetal mortality and morbidity. During pregnancy, estrogen is produced primarily …
Pre-eclampsia and the placenta
CWG Redman - Placenta, 1991 - Elsevier
Pre-eclampsia is a syndrome that is common, dangerous for both mother and baby,
unpredictable in its onset and progression, and untreatable except by terminating the …
unpredictable in its onset and progression, and untreatable except by terminating the …