Deep learning for cellular image analysis

E Moen, D Bannon, T Kudo, W Graf, M Covert… - Nature …, 2019 - nature.com
Recent advances in computer vision and machine learning underpin a collection of
algorithms with an impressive ability to decipher the content of images. These deep learning …

Converting nanotoxicity data to information using artificial intelligence and simulation

X Yan, T Yue, DA Winkler, Y Yin, H Zhu… - Chemical …, 2023 - ACS Publications
Decades of nanotoxicology research have generated extensive and diverse data sets.
However, data is not equal to information. The question is how to extract critical information …

Machine learning model for predicting malaria using clinical information

YW Lee, JW Choi, EH Shin - Computers in biology and medicine, 2021 - Elsevier
Background Rapid diagnosing is crucial for controlling malaria. Various studies have aimed
at develo** machine learning models to diagnose malaria using blood smear images; …

The evolving concept of cell identity in the single cell era

SA Morris - Development, 2019 - journals.biologists.com
Fueled by recent advances in single cell biology, we are moving away from qualitative and
undersampled assessments of cell identity, toward building quantitative, high-resolution cell …

Cell Painting: a decade of discovery and innovation in cellular imaging

S Seal, MA Trapotsi, O Spjuth, S Singh… - Nature …, 2024 - nature.com
Modern quantitative image analysis techniques have enabled high-throughput, high-content
imaging experiments. Image-based profiling leverages the rich information in images to …

[HTML][HTML] Artificial intelligence (AI) in rare diseases: is the future brighter?

S Brasil, C Pascoal, R Francisco, V dos Reis Ferreira… - Genes, 2019 - mdpi.com
The amount of data collected and managed in (bio) medicine is ever-increasing. Thus, there
is a need to rapidly and efficiently collect, analyze, and characterize all this information …

Advances and opportunities in image analysis of bacterial cells and communities

H Jeckel, K Drescher - FEMS Microbiology Reviews, 2021 - academic.oup.com
The cellular morphology and sub-cellular spatial structure critically influence the function of
microbial cells. Similarly, the spatial arrangement of genotypes and phenotypes in microbial …

Image-based high-content screening in drug discovery

S Lin, K Schorpp, I Rothenaigner, K Hadian - Drug discovery today, 2020 - Elsevier
Highlights•Complex phenotypic imaging assays aim at mimicking the biology of
interest.•Cellular profiling in high-content assays improve description of compound …

Review of high-content screening applications in toxicology

S Li, M **a - Archives of toxicology, 2019 - Springer
High-content screening (HCS) technology combining automated microscopy and
quantitative image analysis can address biological questions in academia and the …

High throughput microscopy and single cell phenotypic image-based analysis in toxicology and drug discovery

F Stossi, PK Singh, K Safari, M Marini, D Labate… - Biochemical …, 2023 - Elsevier
Measuring single cell responses to the universe of chemicals (drugs, natural products,
environmental toxicants etc.) is of paramount importance to human health as phenotypic …