Magnetic nanoparticles as MRI contrast agents

A Avasthi, C Caro, E Pozo‑Torres, MP Leal… - … for electrochemical and …, 2020‏ - Springer
Iron oxide nanoparticles (IONPs) have emerged as a promising alternative to conventional
contrast agents (CAs) for magnetic resonance imaging (MRI). They have been extensively …

Biodistribution and targeting properties of iron oxide nanoparticles for treatments of cancer and iron anemia disease

E Alphandéry - Nanotoxicology, 2019‏ - Taylor & Francis
IONP (iron oxide nanoparticles) commercialized for treatments of iron anemia or cancer
diseases can be administered at doses exceeding 1 g per patient, indicating their bio …

Passive targeting of high-grade gliomas via the EPR effect: a closed path for metallic nanoparticles?

C Caro, A Avasthi, JM Paez-Muñoz, MP Leal… - Biomaterials …, 2021‏ - pubs.rsc.org
Passive tumor targeting via the enhanced permeability and retention (EPR) effect has long
been considered the most effective mechanism for the accumulation of nanoparticles inside …

[HTML][HTML] Rational design of magnetic nanoparticles as T1–T2 dual-mode MRI contrast agents

CFGC Geraldes - Molecules, 2024‏ - mdpi.com
Magnetic nanoparticles (MNPs), either paramagnetic or superparamagnetic depending on
their composition and size, have been thoroughly studied as magnetic resonance imaging …

Magnetic nanoparticle-based high-performance positive and negative magnetic resonance imaging contrast agents

T Tegafaw, S Liu, MY Ahmad, AKAA Saidi, D Zhao… - Pharmaceutics, 2023‏ - mdpi.com
In recent decades, magnetic nanoparticles (MNPs) have attracted considerable research
interest as versatile substances for various biomedical applications, particularly as contrast …

Fe3O4-Au Core-Shell Nanoparticles as a Multimodal Platform for In Vivo Imaging and Focused Photothermal Therapy

C Caro, F Gámez, P Quaresma, JM Páez-Muñoz… - Pharmaceutics, 2021‏ - mdpi.com
In this study, we report the synthesis of gold-coated iron oxide nanoparticles capped with
polyvinylpyrrolidone (Fe@ Au NPs). The as-synthesized nanoparticles (NPs) exhibited good …

[HTML][HTML] Bi-Magnetic Core-Shell CoFe2O4@MnFe2O4 Nanoparticles for In Vivo Theranostics

V Nica, C Caro, JM Páez-Muñoz, MP Leal… - Nanomaterials, 2020‏ - mdpi.com
In this work, we report the synthesis and characterization of three magnetic nanosystems,
CoFe2O4, CoFe2O4@ ZnFe2O4, and CoFe2O4@ MnFe2O4, which were developed as …

Smart Design of ZnFe and ZnFe@ Fe Nanoparticles for MRI‐Tracked Magnetic Hyperthermia Therapy: Challenging Classical Theories of Nanoparticles Growth and …

C Caro, C Guzzi, I Moral‐Sánchez… - Advanced …, 2024‏ - Wiley Online Library
Abstract Iron Oxide Nanoparticles (IONPs) hold the potential to exert significant influence on
fighting cancer through their theranostics capabilities as contrast agents (CAs) for magnetic …

Individually stabilized, superparamagnetic nanoparticles with controlled shell and size leading to exceptional stealth properties and high relaxivities

A Lassenberger, A Scheberl, A Stadlbauer… - … applied materials & …, 2017‏ - ACS Publications
Superparamagnetic iron oxide nanoparticles (SPION) have received immense interest for
biomedical applications, with the first clinical application as negative contrast agent in …

Clustering superparamagnetic iron oxide nanoparticles produces organ-targeted high-contrast magnetic resonance images

NJ Hobson, X Weng, B Siow, C Veiga, M Ashford… - …, 2019‏ - Taylor & Francis
Aim: Superparamagnetic iron oxide nanoparticles (SPIONs) have been used as magnetic
resonance imaging (MRI) contrast agents; however, a number of T2-weighted imaging …