Articular cartilage (AC) covers the diarthrodial joints and is responsible for the mechanical
distribution of loads across the joints. The majority of its structure and function is controlled …

Chondrogenesis is a highly coordinated event in embryo development, adult homeostasis,
and repair of the vertebrate cartilage. Fate decisions and differentiation of chondrocytes …

Osteoarthritis (OA) represents a final and common pathway for all major traumatic insults to
synovial joints. OA is the most common form of degenerative joint disease and a major …

Since the discovery of osteoinduction in the early 20th century, innovative biomaterials with
osteoinductive potential have emerged. Over the last 50 years, however, our ability to …

Objective In experimental collagenase‐induced osteoarthritis (OA) in the mouse, synovial
lining macrophages are crucial in mediating joint destruction. It was recently shown that …

Purpose In the present study, the clinical outcomes and second-look arthroscopic findings of
intra-articular injection of stem cells with arthroscopic lavage for treatment of elderly patients …

Objective We investigated the effects of single or repetitive intra-articular injections of
synovial mesenchymal stem cells (MSCs) on a rat osteoarthritis (OA) model, and elucidated …

In this work, articular chondrocytes (ACs) and mesenchymal stem cells (MSCs) with 1: 1 and
1: 3 cell ratios were co-cultured in order to evaluate if a majority of primary ACs can be …

Bone injury repair has always been a tricky problem in clinic, the recent emergence of bone
tissue engineering provides a new direction for the repair of bone injury. However, some …

In recent years, the use of bone marrow mesenchymal stem cell (BMSC) implantation has
provided an alternative treatment for osteoarthritis. The objective of this study is to determine …