[HTML][HTML] Sleep issues in Parkinson's disease and their management

JRP Zuzuárregui, EH During - Neurotherapeutics, 2020‏ - Elsevier
Parkinson's disease (PD) is an alpha-synucleinopathy that leads to prominent motor
symptoms including tremor, bradykinesia, and postural instability. Nonmotor symptoms …

Gender differences and quality of life in Parkinson's disease

P Crispino, M Gino, E Barbagelata… - International journal of …, 2021‏ - mdpi.com
Parkinson's disease has been found to significantly affect health-related quality of life. The
gender differences of the health-related quality of life of subjects with Parkinson's disease …

Impact of advanced Parkinson's disease on caregivers: an international real-world study

P Martinez-Martin, M Skorvanek, T Henriksen… - Journal of …, 2023‏ - Springer
Background Caring for a partner or family member with Parkinson's disease (PD) negatively
affects the caregiver's own physical and emotional well-being, especially those caring for …

Sleep problems affect quality of life in Parkinson's disease along disease progression

C Liguori, V De Franco, R Cerroni, M Spanetta… - Sleep Medicine, 2021‏ - Elsevier
Objectives Non-motor symptoms (NMS) frequently impact health-related quality of life
(HRQoL) in patients with Parkinson's Disease (PD). Sleep problems represent one of the …

Washed microbiota transplantation improves sleep quality in patients with sleep disorder by the gut-brain axis

H He, M Li, Y Qiu, Z Wu, L Wu - Frontiers in Neuroscience, 2024‏ - frontiersin.org
Background The clinical impact of washed microbiota transplantation (WMT) from healthy
donors in sleep disorder (SD) patients is unclear. This study aimed to investigate the effect of …

[HTML][HTML] Can adenosine A2A receptor antagonists be used to treat cognitive impairment, depression or excessive sleepiness in Parkinson's disease?

P Jenner, A Mori, T Kanda - Parkinsonism & Related Disorders, 2020‏ - Elsevier
Abstract Treatment of non-motor symptoms of Parkinson's disease (PD) is a major unmet
need. Targeting adenosine A 2A receptors may address some of the neuropsychiatric …

Parkinson's disease: a narrative review on potential molecular mechanisms of sleep disturbances, REM behavior disorder, and melatonin

MA Samizadeh, H Fallah, M Toomarisahzabi, F Rezaei… - Brain Sciences, 2023‏ - mdpi.com
Parkinson's disease (PD) is one of the most common neurodegenerative diseases. There is
a wide range of sleep disturbances in patients with PD, such as insomnia and rapid eye …

Identifying depression in Parkinson's disease by using combined diffusion tensor imaging and support vector machine

Y Yang, Y Yang, A Pan, Z Xu, L Wang, Y Zhang… - Frontiers in …, 2022‏ - frontiersin.org
Objective To investigate white matter microstructural alterations in Parkinson's disease (PD)
patients with depression using the whole-brain diffusion tensor imaging (DTI) method and to …

Sleep problems are related to a worse quality of life and a greater non-motor symptoms burden in Parkinson's disease

D Santos-García, ES Castro… - Journal of Geriatric …, 2021‏ - journals.sagepub.com
Introduction: The aim of the present study was to examine the frequency of self-reported
sleep problems and their associated factors in a large cohort of PD patients. Methods: PD …

[HTML][HTML] REM sleep behavior disorder and cognitive functions in Parkinson's patients: a systematic review

G Marafioti, F Corallo, D Cardile, G Di Lorenzo… - Journal of Clinical …, 2023‏ - mdpi.com
Sleep disorders, such as REM sleep behavior disorder (RBD) and excessive daytime
sleepiness, are among the most common non-motor symptoms in subjects with Parkinson's …