Müller glia are the major glial component of the retina. They are one of the last retinal cell
types to be born during development, and they function to maintain retinal homeostasis and …

For centuries, philosophers and scientists have been fascinated by the principles and
implications of regeneration in lower vertebrate species. Two features have made zebrafish …

In humans, various genetic defects or age-related diseases, such as diabetic retinopathies,
glaucoma, and macular degeneration, cause the death of retinal neurons and profound …

Adult neurogenesis is a widespread trait of vertebrates; however, the degree of this ability
and the underlying activity of the adult neural stem cells differ vastly among species. In …

Adult zebrafish generate new neurons in the brain and retina throughout life. Growth-related
neurogenesis allows a vigorous regenerative response to damage, and fish can regenerate …

Intense light exposure causes photoreceptor apoptosis in dark-adapted adult albino
zebrafish (Danio rerio). Subsequently, Müller glia increase expression of the Achaete-scute …

Sight is one of our most precious senses. People fear losing their sight more than any other
disability. Thus, restoring sight to the blind is an important goal of vision scientists …

Müller glia function as retinal stem cells in adult zebrafish. In response to loss of retinal
neurons, Müller glia partially dedifferentiate, re-express neuroepithelial markers and re …

The adult central nervous system (CNS) of the zebrafish, owing to its enrichment in
constitutive neurogenic niches, is becoming an increasingly used model to address …

Müller glia (MG) in the zebrafish retina respond to retinal injury by generating multipotent
progenitors for retinal repair. Here, we show that Insulin, Igf-1, and fibroblast growth factor …