Epstein-Barr virus and cancer

MP Thompson, R Kurzrock - Clinical cancer research, 2004 - AACR
EBV was the first human virus to be directly implicated in carcinogenesis. It infects> 90% of
the world's population. Although most humans coexist with the virus without serious …

The Epstein–Barr virus and the pathogenesis of lymphoma

M Vockerodt, LF Yap, C Shannon‐Lowe… - The Journal of …, 2015 - Wiley Online Library
Since the discovery in 1964 of the Epstein–Barr virus (EBV) in African Burkitt lymphoma, this
virus has been associated with a remarkably diverse range of cancer types. Because EBV …

The global health burden of infection‐associated cancers in the year 2002

DM Parkin - International journal of cancer, 2006 - Wiley Online Library
Several infectious agents are considered to be causes of cancer in humans. The fraction of
the different types of cancer, and of all cancers worldwide and in different regions, has been …

Epstein‐Barr virus‐associated Hodgkin's disease: epidemiologic characteristics in international data

SL Glaser, RJ Lin, SL Stewart… - … journal of cancer, 1997 - Wiley Online Library
Hodgkin's disease (HD) has long been suspected to have an infectious precursor, and
indirect evidence has implicated Epstein‐Barr virus (EBV), a ubiquitous herpesvirus, as a …

Human herpesvirus 6

DK Braun, G Dominguez, PE Pellett - Clinical microbiology …, 1997 - Am Soc Microbiol
Human herpesvirus 6 variant A (HHV-6A) and human herpesvirus 6 variant B (HHV-6B) are
two closely related yet distinct viruses. These visuses belong to the Roseolovirus genus of …

Epstein-Barr virus–associated lymphoproliferative disorders

SA Rezk, LM Weiss - Human pathology, 2007 - Elsevier
Epstein-Barr virus (EBV) is a member of the human herpesvirus family that was initially
isolated from a cultured Burkitt lymphoma cell line by Epstein et al in 1964. Subsequent …

An etiological role for the Epstein-Barr virus in the pathogenesis of classical Hodgkin lymphoma

PG Murray, LS Young - Blood, The Journal of the American …, 2019 - ashpublications.org
Although a pathogenic role for the Epstein-Barr virus (EBV) is largely undisputed for tumors
that are consistently EBV genome positive (eg, nasopharyngeal carcinoma, endemic Burkitt …

Expression of LAG-3 by tumor-infiltrating lymphocytes is coincident with the suppression of latent membrane antigen–specific CD8+ T-cell function in Hodgkin …

MK Gandhi, E Lambley, J Duraiswamy, U Dua, C Smith… - Blood, 2006 - ashpublications.org
In Hodgkin lymphoma (HL), the malignant Hodgkin Reed-Sternberg (HRS) cells constitute
only 0.5% of 10% of the diseased tissue. The surrounding cellular infiltrate is enriched with T …

Cancer in Africa 2018: The role of infections

DM Parkin, L Hämmerl, J Ferlay… - International journal of …, 2020 - Wiley Online Library
We estimate the fractions of cancer attributed to infections in Africa in 2018. The number of
new cancer cases occurring was taken from Globocan2018 with some additional …

Hodgkin lymphoma: a review of pathological features and recent advances in pathogenesis

MA Piris, LJ Medeiros, KC Chang - Pathology, 2020 - Elsevier
Hodgkin lymphoma (HL) is composed of two distinct pathological entities, nodular
lymphocyte predominant HL and classic HL, the latter with four subtypes. In contrast with …