Microbiota succession throughout life from the cradle to the grave

C Martino, AH Dilmore, ZM Burcham… - Nature Reviews …, 2022 - nature.com
Associations between age and the human microbiota are robust and reproducible. The
microbial composition at several body sites can predict human chronological age relatively …

Microbiome and cancer

N Cullin, CA Antunes, R Straussman… - Cancer cell, 2021 - cell.com
The human microbiome constitutes a complex multikingdom community that symbiotically
interacts with the host across multiple body sites. Host-microbiome interactions impact …

The human virome: assembly, composition and host interactions

G Liang, FD Bushman - Nature Reviews Microbiology, 2021 - nature.com
The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …

Expanding known viral diversity in the healthy infant gut

SA Shah, L Deng, J Thorsen, AG Pedersen… - Nature …, 2023 - nature.com
The gut microbiome is shaped through infancy and impacts the maturation of the immune
system, thus protecting against chronic disease later in life. Phages, or viruses that infect …

Mutualistic interplay between bacteriophages and bacteria in the human gut

AN Shkoporov, CJ Turkington, C Hill - Nature Reviews Microbiology, 2022 - nature.com
Bacteriophages (phages) are often described as obligate predators of their bacterial hosts,
and phage predation is one of the leading forces controlling the density and distribution of …

A metagenomic catalog of the early-life human gut virome

S Zeng, A Almeida, S Li, J Ying, H Wang, Y Qu… - Nature …, 2024 - nature.com
Early-life human gut microbiome is a pivotal driver of gut homeostasis and infant health.
However, the viral component (known as “virome”) remains mostly unexplored. Here, we …

Transmission and dynamics of mother-infant gut viruses during pregnancy and early life

S Garmaeva, T Sinha, A Gulyaeva, N Kuzub… - Nature …, 2024 - nature.com
Early development of the gut ecosystem is crucial for lifelong health. While infant gut
bacterial communities have been studied extensively, the infant gut virome remains under …

Centenarians have a diverse gut virome with the potential to modulate metabolism and promote healthy lifespan

J Johansen, K Atarashi, Y Arai, N Hirose… - Nature …, 2023 - nature.com
Distinct gut microbiome ecology may be implicated in the prevention of aging-related
diseases as it influences systemic immune function and resistance to infections. Yet, the viral …

[HTML][HTML] The gut virome database reveals age-dependent patterns of virome diversity in the human gut

AC Gregory, O Zablocki, AA Zayed, A Howell… - Cell host & …, 2020 - cell.com
The gut microbiome profoundly affects human health and disease, and their infecting viruses
are likely as important, but often missed because of reference database limitations. Here, we …

PhaTYP: predicting the lifestyle for bacteriophages using BERT

J Shang, X Tang, Y Sun - Briefings in Bioinformatics, 2023 - academic.oup.com
Bacteriophages (or phages), which infect bacteria, have two distinct lifestyles: virulent and
temperate. Predicting the lifestyle of phages helps decipher their interactions with their …