PAMAM dendrimers as efficient drug and gene delivery nanosystems for cancer therapy
Drug delivery systems for cancer chemotherapy are employed to improve the effectiveness
and decrease the side-effects of highly toxic drugs. Most chemotherapy agents have …
and decrease the side-effects of highly toxic drugs. Most chemotherapy agents have …
[HTML][HTML] Designing enhanced spray dried particles for inhalation: A review of the impact of excipients and processing parameters on particle properties
Spray drying is a constructive single-step manufacturing technique used to produce dry
powder. Spray drying plays a remarkable role in producing inhalable powder formulations …
powder. Spray drying plays a remarkable role in producing inhalable powder formulations …
Co-delivery of curcumin and Bcl-2 siRNA by PAMAM dendrimers for enhancement of the therapeutic efficacy in HeLa cancer cells
Co-delivery of therapeutic agents and small interfering RNA (siRNA) can be achieved by a
suitable nanovehicle. In this work, the solubility and bioavailability of curcumin (Cur) were …
suitable nanovehicle. In this work, the solubility and bioavailability of curcumin (Cur) were …
[HTML][HTML] Perspectives of nano-carrier drug delivery systems to overcome cancer drug resistance in the clinics
A Ulldemolins, J Seras-Franzoso, F Andrade… - Cancer Drug …, 2021 - ncbi.nlm.nih.gov
Advanced cancer is still considered an incurable disease because of its metastatic spread to
distal organs and progressive gain of chemoresistance. Even though considerable treatment …
distal organs and progressive gain of chemoresistance. Even though considerable treatment …
Molecular targeting of epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor (VEGFR)
Epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor
(VEGFR) are two extensively studied membrane-bound receptor tyrosine kinase proteins …
(VEGFR) are two extensively studied membrane-bound receptor tyrosine kinase proteins …
A recent update: solid lipid nanoparticles for effective drug delivery
S Pandey, F Shaikh, A Gupta… - Advanced …, 2021 - pmc.ncbi.nlm.nih.gov
Solid lipid nanoparticles (SLNs) are one of the developed technologies for addressing the
bioavailability and targeting issues of drug delivery. In this review article, we attempted to …
bioavailability and targeting issues of drug delivery. In this review article, we attempted to …
A comprehensive overview of dry powder inhalers for pulmonary drug delivery: Challenges, advances, optimization techniques, and applications
Dry powder inhaler (DPI) is an attractive dosage form for local and systemic pulmonary drug
delivery. However, designing DPIs with adequate physicochemical properties is …
delivery. However, designing DPIs with adequate physicochemical properties is …
Ethambutol-loaded solid lipid nanoparticles as dry powder inhalable formulation for tuberculosis therapy
E Nemati, A Mokhtarzadeh, V Panahi-Azar… - AAPS …, 2019 - Springer
Ethambutol hydrocloride (EMB) is an anti-tuberculosis drug, which is commonly used as a
protection agent against of unrecognized resistance to other drugs employed to treat this …
protection agent against of unrecognized resistance to other drugs employed to treat this …
Co-Delivery of erlotinib and resveratrol via nanostructured lipid Carriers: a synergistically promising approach for cell proliferation prevention and ROS-Mediated …
Cancer treatments are always associated with various challenges, and scientists are
constantly trying to find new therapies and methods. Erlotinib (ELT) is a well-known …
constantly trying to find new therapies and methods. Erlotinib (ELT) is a well-known …
[HTML][HTML] Improving breast cancer therapy using doxorubicin loaded solid lipid nanoparticles: Synthesis of a novel arginine-glycine-aspartic tripeptide conjugated, pH …
G Zheng, M Zheng, B Yang, H Fu, Y Li - Biomedicine & pharmacotherapy, 2019 - Elsevier
Breast cancer is the leading cause of cancer mortality in women worldwide. To overcome
the toxic side effects and multidrug resistance (MDR) during doxorubicin (DOX) …
the toxic side effects and multidrug resistance (MDR) during doxorubicin (DOX) …