PAMAM dendrimers as efficient drug and gene delivery nanosystems for cancer therapy

F Abedi-Gaballu, G Dehghan, M Ghaffari, R Yekta… - Applied materials …, 2018 - Elsevier
Drug delivery systems for cancer chemotherapy are employed to improve the effectiveness
and decrease the side-effects of highly toxic drugs. Most chemotherapy agents have …

[HTML][HTML] Designing enhanced spray dried particles for inhalation: A review of the impact of excipients and processing parameters on particle properties

N Alhajj, NJ O'Reilly, H Cathcart - Powder Technology, 2021 - Elsevier
Spray drying is a constructive single-step manufacturing technique used to produce dry
powder. Spray drying plays a remarkable role in producing inhalable powder formulations …

Co-delivery of curcumin and Bcl-2 siRNA by PAMAM dendrimers for enhancement of the therapeutic efficacy in HeLa cancer cells

M Ghaffari, G Dehghan, B Baradaran… - Colloids and Surfaces B …, 2020 - Elsevier
Co-delivery of therapeutic agents and small interfering RNA (siRNA) can be achieved by a
suitable nanovehicle. In this work, the solubility and bioavailability of curcumin (Cur) were …

[HTML][HTML] Perspectives of nano-carrier drug delivery systems to overcome cancer drug resistance in the clinics

A Ulldemolins, J Seras-Franzoso, F Andrade… - Cancer Drug …, 2021 - ncbi.nlm.nih.gov
Advanced cancer is still considered an incurable disease because of its metastatic spread to
distal organs and progressive gain of chemoresistance. Even though considerable treatment …

Molecular targeting of epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor (VEGFR)

NEM Kaufman, S Dhingra, SD Jois, MGH Vicente - Molecules, 2021 - mdpi.com
Epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor
(VEGFR) are two extensively studied membrane-bound receptor tyrosine kinase proteins …

A recent update: solid lipid nanoparticles for effective drug delivery

S Pandey, F Shaikh, A Gupta… - Advanced …, 2021 - pmc.ncbi.nlm.nih.gov
Solid lipid nanoparticles (SLNs) are one of the developed technologies for addressing the
bioavailability and targeting issues of drug delivery. In this review article, we attempted to …

A comprehensive overview of dry powder inhalers for pulmonary drug delivery: Challenges, advances, optimization techniques, and applications

HI Shahin, L Chablani - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
Dry powder inhaler (DPI) is an attractive dosage form for local and systemic pulmonary drug
delivery. However, designing DPIs with adequate physicochemical properties is …

Ethambutol-loaded solid lipid nanoparticles as dry powder inhalable formulation for tuberculosis therapy

E Nemati, A Mokhtarzadeh, V Panahi-Azar… - AAPS …, 2019 - Springer
Ethambutol hydrocloride (EMB) is an anti-tuberculosis drug, which is commonly used as a
protection agent against of unrecognized resistance to other drugs employed to treat this …

Co-Delivery of erlotinib and resveratrol via nanostructured lipid Carriers: a synergistically promising approach for cell proliferation prevention and ROS-Mediated …

L Asadollahi, A Mahoutforoush, SS Dorreyatim… - International journal of …, 2022 - Elsevier
Cancer treatments are always associated with various challenges, and scientists are
constantly trying to find new therapies and methods. Erlotinib (ELT) is a well-known …

[HTML][HTML] Improving breast cancer therapy using doxorubicin loaded solid lipid nanoparticles: Synthesis of a novel arginine-glycine-aspartic tripeptide conjugated, pH …

G Zheng, M Zheng, B Yang, H Fu, Y Li - Biomedicine & pharmacotherapy, 2019 - Elsevier
Breast cancer is the leading cause of cancer mortality in women worldwide. To overcome
the toxic side effects and multidrug resistance (MDR) during doxorubicin (DOX) …