The role of long non-coding RNAs (lncRNAs) in the development and progression of fibrosis associated with nonalcoholic fatty liver disease (NAFLD)

A Hanson, D Wilhelmsen, JK DiStefano - Non-coding RNA, 2018 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of conditions ranging
from hepatic steatosis to inflammation (nonalcoholic steatohepatitis or NASH) with or without …

Hepatitis C virus associated hepatocellular carcinoma

M Khatun, R Ray, RB Ray - Advances in cancer research, 2021 - Elsevier
Liver cancer is a global problem and hepatocellular carcinoma (HCC) accounts for about
85% of this cancer. In the USA, etiologies and risk factors for HCC include chronic hepatitis …

Nuclear-encoded lncRNA MALAT1 epigenetically controls metabolic reprogramming in HCC cells through the mitophagy pathway

Y Zhao, L Zhou, H Li, T Sun, X Wen, X Li… - … Therapy-Nucleic Acids, 2021 - cell.com
Mitochondrial dysfunction is a metabolic hallmark of cancer cells. In search of molecular
factors involved in this dysregulation in hepatocellular carcinoma (HCC), we found that the …

Long noncoding RNA MALAT1 inhibits the apoptosis and autophagy of hepatocellular carcinoma cell by targeting the microRNA-146a/PI3K/Akt/mTOR axis

N Peng, J He, J Li, H Huang, W Huang, Y Liao… - Cancer Cell …, 2020 - Springer
Background Increased long noncoding RNA (lncRNA) expression is characteristic to
hepatocellular carcinoma (HCC) and several other neoplasms. The present study aimed to …

CircZFR promotes hepatocellular carcinoma progression through regulating miR-3619–5p/CTNNB1 axis and activating Wnt/β-catenin pathway

A Tan, Q Li, L Chen - Archives of biochemistry and biophysics, 2019 - Elsevier
Circular RNAs (circRNAs) have been discovered to exert essential roles in human cancers,
including hepatocellular carcinoma. Although circZFR has been reported to facilitate the …

miR‐211 sponges lncRNA MALAT1 to suppress tumor growth and progression through inhibiting PHF19 in ovarian carcinoma

F Tao, X Tian, S Ruan, M Shen, Z Zhang - The FASEB Journal, 2018 - Wiley Online Library
Accumulating evidence has indicated that microRNAs (miRNAs) play an important role in
the occurrence and progression of ovarian cancer (OC). However, the function of miRNAs …

A circulating long noncoding RNA panel serves as a diagnostic marker for hepatocellular carcinoma

J Huang, Y Zheng, X **ao, C Liu, J Lin… - Disease …, 2020 - Wiley Online Library
Background. Circulating long noncoding RNAs (lncRNAs) have been demonstrated to serve
as diagnostic biomarkers for various cancers. We aimed to elucidate the diagnostic efficacy …

LncRNAs in HCV infection and HCV-related liver disease

JP Unfried, P Fortes - International Journal of Molecular Sciences, 2020 - mdpi.com
Long non-coding RNAs (lncRNAs) are transcripts with poor coding capacity that may interact
with proteins, DNA, or other RNAs to perform structural and regulatory functions. The …

[PDF][PDF] Long noncoding RNA MALAT1 regulates hepatocellular carcinoma growth under hypoxia via sponging MicroRNA-200a

ZB Zhao, F Chen, XF Bai - Yonsei Medical Journal, 2019 - synapse.koreamed.org
Purpose Hepatocellular carcinoma (HCC) is a common cancer worldwide. Metastasis-
associated lung adenocarcinoma transcript 1 (MALAT1), a long noncoding RNA (lncRNA) …