Large animal models in regenerative medicine and tissue engineering: to do or not to do
I Ribitsch, PM Baptista, A Lange-Consiglio… - … in Bioengineering and …, 2020 - frontiersin.org
Rapid developments in Regenerative Medicine and Tissue Engineering has witnessed an
increasing drive toward clinical translation of breakthrough technologies. However, the …
increasing drive toward clinical translation of breakthrough technologies. However, the …
Equine asthma: current understanding and future directions
The 2019 Havemeyer Workshop brought together researchers and clinicians to discuss the
latest information on Equine Asthma and provide future research directions. Current clinical …
latest information on Equine Asthma and provide future research directions. Current clinical …
Asthma: the use of animal models and their translational utility
Asthma is characterized by chronic lower airway inflammation that results in airway
remodeling, which can lead to a permanent decrease in lung function. The pathophysiology …
remodeling, which can lead to a permanent decrease in lung function. The pathophysiology …
Heaves, an asthma‐like disease of horses
M Leclere, A LAVOIE‐LAMOUREUX, JP LAVOIE - Respirology, 2011 - Wiley Online Library
Animal models have been developed to investigate specific components of asthmatic airway
inflammation, hyper‐responsiveness or remodelling. However, all of these aspects are …
inflammation, hyper‐responsiveness or remodelling. However, all of these aspects are …
Asthma “of horses and men”—How can equine heaves help us better understand human asthma immunopathology and its functional consequences?
Animal models have been studied to unravel etiological, immunopathological, and genetic
attributes leading to asthma. However, while experiments in which the disease is artificially …
attributes leading to asthma. However, while experiments in which the disease is artificially …
Recurrent airway obstruction: a review
RS Pirie - Equine veterinary journal, 2014 - Wiley Online Library
Recurrent airway obstruction is a widely recognised airway disorder, characterised by
hypersensitivity‐mediated neutrophilic airway inflammation and lower airway obstruction in …
hypersensitivity‐mediated neutrophilic airway inflammation and lower airway obstruction in …
The contribution of oxidative stress and inflamm-aging in human and equine asthma
Aging is associated with a dysregulation of the immune system, leading to a general pro-
inflammatory state of the organism, a process that has been named inflamm-aging …
inflammatory state of the organism, a process that has been named inflamm-aging …
Bronchoalveolar lavage: sampling technique and guidelines for cytologic preparation and interpretation
AM Hoffman - Veterinary Clinics of North America: Equine Practice, 2008 - Elsevier
Bronchoalveolar lavage (BAL) is a method for the recovery of respiratory secretions that line
the peripheral airways and alveoli. Overall, BAL is considered very safe and sufficiently …
the peripheral airways and alveoli. Overall, BAL is considered very safe and sufficiently …
The immune mechanisms of severe equine asthma—Current understanding and what is missing
Simple Summary Severe equine asthma (sEA) is a highly prevalent respiratory disease
affecting adult horses. Affected horses present with cough, nasal discharge and increased …
affecting adult horses. Affected horses present with cough, nasal discharge and increased …
Neutrophil extracellular traps are found in bronchoalveolar lavage fluids of horses with severe asthma and correlate with asthma severity
P Janssen, I Tosi, A Hego, P Maréchal… - Frontiers in …, 2022 - frontiersin.org
Asthma encompasses a spectrum of heterogenous immune-mediated respiratory disorders
sharing a similar clinical pattern characterized by cough, wheeze and exercise intolerance …
sharing a similar clinical pattern characterized by cough, wheeze and exercise intolerance …