Biotechnology is playing a vital alternative role in the production of pharmaceutical plant
secondary metabolites to support industrial production and mitigate over-exploitation of …

Biologically Significant and Recently Isolated Alkaloids from Endophytic Fungi | Journal of
Natural Products Recently Viewedclose modal Pair your accounts. Export articles to Mendeley …

Camptothecin and 10-hydroxycamptothecin are two important precursors for the synthesis of
the clinically useful anticancer drugs, topotecan and irinotecan. In recent years, efforts have …

In this study, the production of camptothecine and its derivatives, in thirteen species of the
family Icacinaceae, namely, Apodytes dimidiata, Codiocarpus andamanicus, Gomphandra …

Camptothecin (CPT), a monoterpene alkaloid, is an important anticancer compound
obtained from several plant sources including Camptotheca acuminta (from China) and …

Endophytic fungi, a group of fungi living inside the host plant tissues without caus ing visible
symptoms of disease, are known to occur ubiquitously in plants'. Existing in a mutualistic …

Background Camptothecin (CPT), a quinoline alkaloid, is a potent inhibitor of eukaryotic
topoisomerase I. Because of this property, several derivatives of CPT are used as …

Camptothecin (CPT) and its analogs are gaining prominence for its promising anti-cancer
activity and are used throughout the world for the treatment of colorectal, breast, and lung …

Key message Comprehensive transcriptome analysis of leaf and root tissues of
Nothapodytes nimmoniana unravels several putative pathway genes, transcription factors …

Nothapodytes nimmoniana (Icacinaceae) yields camptothecin (isoquinoline alkaloid) which
is a potent anti-cancer drug. The major objectives of the present study were to develop an …