In vivo cancer-based functional genomics

C Li, AL Kasinski - Trends in cancer, 2020 - cell.com
Pinpointing the underlying mechanisms that drive tumorigenesis in human patients is a
prerequisite for identifying suitable therapeutic targets for precision medicine. In contrast to …

[HTML][HTML] Clustering of chromatin remodeling enzymes predicts prognosis and clinical benefit of therapeutic strategy in pancreatic cancer

HC Wang, HY Shih, CC Wu, LT Chen… - … Journal of Medical …, 2022 - ncbi.nlm.nih.gov
In recent years, translational research and pharmacological targeting of epigenetic
modifications have become the focus of personalized therapy for patients with pancreatic …

In-Cell Western Protocol for Semi-High-Throughput Screening of Single Clones

AS Pal, AM Agredo, AL Kasinski - Bio-protocol, 2022 - bio-protocol.org
The in-cell western (ICW) is an immunocytochemical technique that has been used to
screen for effects of siRNAs, drugs, and small molecule inhibitors. The reduced time and …