Estrogen deficiency and the origin of obesity during menopause

F Lizcano, G Guzmán - BioMed research international, 2014 - Wiley Online Library
Sex hormones strongly influence body fat distribution and adipocyte differentiation.
Estrogens and testosterone differentially affect adipocyte physiology, but the importance of …

The role of estrogens in control of energy balance and glucose homeostasis

F Mauvais-Jarvis, DJ Clegg, AL Hevener - Endocrine reviews, 2013 - academic.oup.com
Estrogens play a fundamental role in the physiology of the reproductive, cardiovascular,
skeletal, and central nervous systems. In this report, we review the literature in both rodents …

Sex differences in the physiology of eating

L Asarian, N Geary - American Journal of Physiology …, 2013 - journals.physiology.org
Hypothalamic-pituitary-gonadal (HPG) axis function fundamentally affects the physiology of
eating. We review sex differences in the physiological and pathophysiological controls of …

Sex-specific differences in lipid and glucose metabolism

O Varlamov, CL Bethea, CT Roberts Jr - Frontiers in endocrinology, 2015 - frontiersin.org
Energy metabolism in humans is tuned to distinct sex-specific functions that potentially
reflect the unique requirements in females for gestation and lactation, whereas male …

The hypothalamus for whole-body physiology: from metabolism to aging

T Liu, Y Xu, CX Yi, Q Tong, D Cai - Protein & Cell, 2022 - academic.oup.com
Obesity and aging are two important epidemic factors for metabolic syndrome and many
other health issues, which contribute to devastating diseases such as cardiovascular …

Modulation of appetite by gonadal steroid hormones

L Asarian, N Geary - … Transactions of the Royal Society B …, 2006 - royalsocietypublishing.org
Several sex differences in eating, their control by gonadal steroid hormones and their
peripheral and central mediating mechanisms are reviewed. Adult female rats and mice as …

Sex differences in obesity and the regulation of energy homeostasis

JC Lovejoy, A Sainsbury… - Obesity …, 2009 - Wiley Online Library
Obesity prevalence is generally higher in women than in men, and there is also a sex
difference in body fat distribution. Sex differences in obesity can be explained in part by the …

Estrogen and androgen receptors: regulators of fuel homeostasis and emerging targets for diabetes and obesity

F Mauvais-Jarvis - Trends in Endocrinology & Metabolism, 2011 - cell.com
Because of increasing life expectancy, the contribution of age-related estrogen or androgen
deficiency to obesity and type 2 diabetes will become a new therapeutic challenge. This …

Central effects of estradiol in the regulation of food intake, body weight, and adiposity

LM Brown, DJ Clegg - The Journal of steroid biochemistry and molecular …, 2010 - Elsevier
In recent years, obesity and its associated health disorders and costs have increased.
Accumulation of adipose tissue, or fat, in the intra-abdominal adipose depot is associated …

Sex as a biological variable in nutrition research: from human studies to animal models

Y Chen, M Kim, S Paye… - Annual review of …, 2022 - annualreviews.org
Biological sex is a fundamental source of phenotypic variability across species. Males and
females have different nutritional needs and exhibit differences in nutrient digestion and …