How Caenorhabditis elegans Senses Mechanical Stress, Temperature, and Other Physical Stimuli

MB Goodman, P Sengupta - Genetics, 2019 - academic.oup.com
Caenorhabditis elegans lives in a complex habitat in which they routinely experience large
fluctuations in temperature, and encounter physical obstacles that vary in size and …

Investigating the molecular mechanisms of learning and memory using Caenorhabditis elegans

A Rahmani, YL Chew - Journal of Neurochemistry, 2021 - Wiley Online Library
Learning is an essential biological process for survival since it facilitates behavioural
plasticity in response to environmental changes. This process is mediated by a wide variety …

Molecular encoding of stimulus features in a single sensory neuron type enables neuronal and behavioral plasticity

N Harris, SG Bates, Z Zhuang, M Bernstein… - Current biology, 2023 - cell.com
Neurons modify their transcriptomes in response to an animal's experience. How specific
experiences are transduced to modulate gene expression and precisely tune neuronal …

Maturation and clearance of autophagosomes in neurons depends on a specific cysteine protease isoform, ATG-4.2

SE Hill, KJ Kauffman, M Krout, JE Richmond, TJ Melia… - Developmental cell, 2019 - cell.com
In neurons, defects in autophagosome clearance have been associated with
neurodegenerative disease. Yet, the mechanisms that coordinate trafficking and clearance …

Integration of plasticity mechanisms within a single sensory neuron of C. elegans actuates a memory

JD Hawk, AC Calvo, P Liu, A Almoril-Porras, A Aljobeh… - Neuron, 2018 - cell.com
Neural plasticity, the ability of neurons to change their properties in response to
experiences, underpins the nervous system's capacity to form memories and actuate …

[HTML][HTML] The neural basis of heat seeking in a human-infective parasitic worm

AS Bryant, F Ruiz, JH Lee, EA Hallem - Current Biology, 2022 - cell.com
Soil-transmitted parasitic nematodes infect over one billion people and cause devastating
morbidity worldwide. Many of these parasites have infective larvae that locate hosts using …

Automated and controlled mechanical stimulation and functional imaging in vivo in C. elegans

Y Cho, DA Porto, H Hwang, LJ Grundy, WR Schafer… - Lab on a Chip, 2017 - pubs.rsc.org
C. elegans is a useful genetic model system for investigating mechanisms involved in
sensory behavior which are potentially relevant to human diseases. While utilities of …