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A forward vision for chemodynamic therapy: issues and opportunities
Since the insight to fuse Fenton chemistry and nanomedicine into cancer therapy, great
signs of progress have been made in the field of chemodynamic therapy (CDT). However …
signs of progress have been made in the field of chemodynamic therapy (CDT). However …
The therapeutic potential of targeting regulated non-apoptotic cell death
Cell death is critical for the development and homeostasis of almost all multicellular
organisms. Moreover, its dysregulation leads to diverse disease states. Historically …
organisms. Moreover, its dysregulation leads to diverse disease states. Historically …
Ferroptosis of tumour neutrophils causes immune suppression in cancer
Ferroptosis is a non-apoptotic form of regulated cell death that is triggered by the
discoordination of regulatory redox mechanisms culminating in massive peroxidation of …
discoordination of regulatory redox mechanisms culminating in massive peroxidation of …
[HTML][HTML] Cuproptosis: A novel therapeutic target for overcoming cancer drug resistance
Cuproptosis is a newly identified form of cell death driven by copper. Recently, the role of
copper and copper triggered cell death in the pathogenesis of cancers have attracted …
copper and copper triggered cell death in the pathogenesis of cancers have attracted …
Overcoming cancer chemotherapy resistance by the induction of ferroptosis
Y Wang, X Wu, Z Ren, Y Li, W Zou, J Chen… - Drug Resistance …, 2023 - Elsevier
Abstract Development of resistance to chemotherapy in cancer continues to be a major
challenge in cancer management. Ferroptosis, a unique type of cell death, is mechanistically …
challenge in cancer management. Ferroptosis, a unique type of cell death, is mechanistically …
Recent progress of supramolecular chemotherapy based on host–guest interactions
Chemotherapy is widely recognized as an effective approach for treating cancer due to its
ability to eliminate cancer cells using chemotherapeutic drugs. However, traditional …
ability to eliminate cancer cells using chemotherapeutic drugs. However, traditional …
ROS induced lipid peroxidation and their role in ferroptosis
HT Endale, W Tesfaye, TA Mengstie - Frontiers in cell and …, 2023 - frontiersin.org
Reactive oxygen species (ROS) play a crucial part in the process of cell death, including
apoptosis, autophagy, and ferroptosis. ROS involves in the oxidation of lipids and generate …
apoptosis, autophagy, and ferroptosis. ROS involves in the oxidation of lipids and generate …
Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases
Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism
Ferroptosis is mediated by lipid peroxidation of phospholipids containing polyunsaturated
fatty acyl moieties. Glutathione, the key cellular antioxidant capable of inhibiting lipid …
fatty acyl moieties. Glutathione, the key cellular antioxidant capable of inhibiting lipid …
[HTML][HTML] Inhibition of ferroptosis and iron accumulation alleviates pulmonary fibrosis in a bleomycin model
Z Pei, Y Qin, X Fu, F Yang, F Huo, X Liang, S Wang… - Redox biology, 2022 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease characterized by
excessive proliferation of fibroblasts and excessive accumulation of extracellular matrix …
excessive proliferation of fibroblasts and excessive accumulation of extracellular matrix …