How to deal with parameters for whole-cell modelling

AC Babtie, MPH Stumpf - Journal of The Royal Society …, 2017 - royalsocietypublishing.org
Dynamical systems describing whole cells are on the verge of becoming a reality. But as
models of reality, they are only useful if we have realistic parameters for the molecular …

Causal deep learning: encouraging impact on real-world problems through causality

J Berrevoets, K Kacprzyk, Z Qian… - … and Trends® in …, 2024 - nowpublishers.com
Causality has the potential to truly transform the way we solve a large number of real-world
problems. Yet, so far, its potential largely remains to be unlocked as causality often requires …

Inferring biological networks by sparse identification of nonlinear dynamics

NM Mangan, SL Brunton, JL Proctor… - IEEE Transactions on …, 2016 - ieeexplore.ieee.org
Inferring the structure and dynamics of network models is critical to understanding the
functionality and control of complex systems, such as metabolic and regulatory biological …

NSCGRN: a network structure control method for gene regulatory network inference

W Liu, X Sun, L Yang, K Li, Y Yang… - Briefings in …, 2022 - academic.oup.com
Accurate inference of gene regulatory networks (GRNs) is an essential premise for
understanding pathogenesis and curing diseases. Various computational methods have …

Network-based approaches for analysis of complex biological systems

D Chasman, AF Siahpirani, S Roy - Current opinion in biotechnology, 2016 - Elsevier
Cells function and respond to changes in their environment by the coordinated activity of
their molecular components, including mRNAs, proteins and metabolites. At the heart of …