Objective The purpose of this study was to explore the diagnostic yield and clinical utility of
trio‐based rapid whole exome sequencing (rWES) in pregnancies of fetuses with a wide …

The origin of ICEF remains unclear. It is considered a normal developmental variant, but
either inflammatory or hypoxic processes could be involved in its appearance. In low-risk …

Various soft markers can be detected in the ultrasonography of foetuses, which can be
related to chromosomal abnormalities and increases the risk of abnormalities, or they can be …

Multiple pieces of evidence support the prenatal predisposition of autism spectrum disorder
(ASD). Nevertheless, robust data about abnormalities in foetuses later develo** into …

Antenatal screening for maternal and fetal health is a rapidly evolving field crucial in
obstetric care. Various diagnostic and therapeutic options have emerged to address various …

Objective Fetuses with abnormal karyotypes often exhibit distinctive ultrasonographic
markers, including major anomalies and “soft” markers, indicating potential chromosomal …

Purpose To determine long-term outcome of infants with isolated or multiple soft markers but
no structural or chromosomal abnormalities. Methods A retrospective study of 78 pregnant …

Background: Although soft markers may be seen as normal variants, they are important due
to their association with chromosomal and congenital abnormalities. Methods: This cross …

Second trimester ultrasound examination for risk assessment of chromosomal abnormalities
remains an important component of prenatal evaluation. We have conducted a retrospective …

Einleitung: Aufgrund verbesserter hochauflösender Ultraschall-Geräte können viele
Organauffälligkeiten bereits im Ersttrimester-Screening detektiert werden. Ziel dieser Studie …