Neural modulation with photothermally active nanomaterials

Y Wang, R Garg, D Cohen-Karni… - Nature Reviews …, 2023 - nature.com
Modulating neural electrophysiology with high precision is essential for understanding
neural communication and for the diagnosis and treatment of neural disorders. Photothermal …

Distributed dopaminergic signaling in the basal ganglia and its relationship to motor disability in Parkinson's disease

S Zhai, Q Cui, DNV Simmons, DJ Surmeier - Current opinion in …, 2023 - Elsevier
The degeneration of mesencephalic dopaminergic neurons that innervate the basal ganglia
is responsible for the cardinal motor symptoms of Parkinson's disease (PD). It has been …

Distinct reward processing by subregions of the nucleus accumbens

G Chen, S Lai, G Bao, J Ke, X Meng, S Lu, X Wu, H Xu… - Cell Reports, 2023 - cell.com
The nucleus accumbens (NAc) plays an important role in motivation and reward processing.
Recent studies suggest that different NAc subnuclei differentially contribute to reward …

Neuronal and synaptic adaptations underlying the benefits of deep brain stimulation for Parkinson's disease

W Xu, J Wang, XN Li, J Liang, L Song, Y Wu… - Translational …, 2023 - Springer
Deep brain stimulation (DBS) is a well-established and effective treatment for patients with
advanced Parkinson's disease (PD), yet its underlying mechanisms remain enigmatic …

Characterization of graded 6-Hydroxydopamine unilateral lesion in medial forebrain bundle of mice

J Cui, D Zhao, M Xu, Z Li, J Qian, N Song, J Wang… - Scientific reports, 2024 - nature.com
Parkinson's disease (PD) is the second most common age-related neurodegenerative
disease, with a progressive loss of dopaminergic cells and fibers. The purpose of this study …

[HTML][HTML] Changed firing activity of nigra dopaminergic neurons in Parkinson's disease

XY Chen, C Liu, Y Xue, L Chen - Neurochemistry International, 2023 - Elsevier
Parkinson's disease is the second most common neurodegenerative disease which is
characterized by selective degeneration of dopaminergic neurons in the substantia nigra …

[HTML][HTML] Connectivity of the corticostriatal and thalamostriatal systems in normal and parkinsonian states: an update

AC Martel, A Galvan - Neurobiology of disease, 2022 - Elsevier
The striatum receives abundant glutamatergic afferents from the cortex and thalamus. These
inputs play a major role in the functions of the striatal neurons in normal conditions, and are …

[HTML][HTML] Particulate matter induces depression-like behavior through systemic inflammation and brain-derived neurotrophic factors

H Li, X Guo, P Li, X Gao, X Song, X Chen… - Environment …, 2024 - Elsevier
Particulate matter (PM) has always received widespread attention, PM2. 5 pollution is
associated with many adverse effects, including cardiovascular, respiratory and metabolic …

Updates on brain regions and neuronal circuits of movement disorders in Parkinson's disease

J Wang, X Wang, H Li, L Shi, N Song, J **e - Ageing Research Reviews, 2023 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative disease with a global burden
that affects more often in the elderly. The basal ganglia (BG) is believed to account for …

Genetically engineered mesenchymal stem cells with dopamine synthesis for Parkinson's disease in animal models

J Li, N Li, J Wei, C Feng, Y Chen, T Chen, Z Ai… - npj Parkinson's …, 2022 - nature.com
Although striatal delivery of three critical genes for dopamine synthesis by viruses is a
potential clinical approach for treating Parkinson's disease (PD), the approach makes it …