Engineering signalling pathways in mammalian cells

AV Leopold, VV Verkhusha - Nature biomedical engineering, 2024 - nature.com
In mammalian cells, signalling pathways orchestrate cellular growth, differentiation and
survival, as well as many other processes that are essential for the proper functioning of …

Design of programmable post-translational switch control platform for on-demand protein secretion in mammalian cells

M Mansouri, PG Ray, N Franko, S Xue… - Nucleic Acids …, 2023 - academic.oup.com
The development of novel strategies to program cellular behaviors is a central goal in
synthetic biology, and post-translational control mediated by engineered protein circuits is a …

The cyclic peptide G4CP2 enables the modulation of galactose metabolism in yeast by interfering with GAL4 transcriptional activity

S Rosa, A Tagliani, C Bertaso, L Tadini… - Frontiers in Molecular …, 2023 - frontiersin.org
Genetically-encoded combinatorial peptide libraries are convenient tools to identify peptides
to be used as therapeutics, antimicrobials and functional synthetic biology modules. Here …

[PDF][PDF] An Extended Feature Representation Technique for Predicting Sequenced-based Host-pathogen Protein-protein Interaction

J Emmanuel, I Isewon, G Olasehinde, J Oyelade - Machine learning, 2025 - core.ac.uk
Background: The use of machine learning models in sequence-based Protein-Protein
Interaction prediction typically requires the conversion of amino acid sequences into feature …

基于多层功能结构的谷物蛋白质功能预测.

沈婷婷, 刘静, 管骁 - Transactions of the Chinese Society of …, 2023 - search.ebscohost.com
为使研究人员可以更加便捷, 准确地选择功能蛋白质, 更高效完成谷物功能性食品的研发与创新,
该研究提出基于多层功能结构的谷物蛋白质功能预测方法. 该研究首先构建多种谷物数据共建的 …

Synthetic Genetic Elements, Devices, and Systems

Y Kato, C Lou - Life, 2022 - mdpi.com
Since the beginning of life on Earth, over the course of 3 to 4 billion years, nature has
created vast quantities of genetic elements. These freshly created elements faced natural …

Understanding and Utilizing Protein Interactions in Diverse Environments

KL Swingle - 2022 - search.proquest.com
Transient protein-protein and protein-molecule interactions fluctuate between associated
and dissociated states. They are widespread in nature and mediate most biological …

[HTML][HTML] Synthetic Biology: Extraordinarily Advanced Systems

ZN Koyuncu, ND Çalışkan - bioinfocodes.com
With the advancement of technology, there has been a tremendous expansion of scientific
knowledge. This flow of information has led to the emergence of interdisciplinary fields such …