Parkinson's Disease: Advances in Treatment and the Syntheses of Various Classes of Pharmaceutical Drug Substances

DR Hill, AD Huters, TB Towne, RE Reddy… - Chemical …, 2023 - ACS Publications
An overview of Parkinson's disease (PD) prevalence, diagnosis, and currently available
treatment options is provided. A comprehensive list of different classes of marketed …

Recent progress in the nitration of arenes and alkenes

YE Qian, L Zheng, HY **ang, H Yang - Organic & Biomolecular …, 2021 - pubs.rsc.org
Nitro compounds are a predominant class of synthetic intermediates and building blocks for
the preparation of a wide range of nitrogen-containing compounds in the chemical industry …

Organic nitrating reagents

S Patra, I Mosiagin, R Giri, D Katayev - Synthesis, 2022 - thieme-connect.com
Nitro compounds are vital raw chemicals that are widely used in academic laboratories and
industries for the preparation of various drugs, agrochemicals, and materials. Thus, nitrating …

Electrochemical nitration with nitrite

SP Blum, C Nickel, L Schäffer, T Karakaya… - …, 2021 - Wiley Online Library
Aromatic nitration has tremendous importance in organic chemistry as nitroaromatic
compounds serve as versatile building blocks. This study represents the electrochemical …

Reduced estrogenic risks of a sunscreen additive: Theoretical design and evaluation of functionally improved salicylates

Y Cui, W He, Z Wang, H Yang, M Zheng, Y Li - Journal of Hazardous …, 2024 - Elsevier
Salicylic esters (SEs), the widely used ultraviolet (UV) absorbers in sunscreen products,
have been found to have health risks such as skin sensitization and estrogenic effects. This …

Recent Progress in the Synthesis of Drugs and Bioactive Molecules Incorporating Nitro (het) arene Core

M Bastrakov, A Starosotnikov - Pharmaceuticals, 2022 - mdpi.com
Aromatic nitro compounds play a unique role in the synthesis of drugs and pharmaceutically
oriented molecules. This field of organic chemistry continues to be in demand and relevant …

Nitration of Derivatives of Imidazo[1,5‐a]pyridine via C−H Functionalization with Fe(NO3)3 ⋅ 9H2O as a Promoter and a Nitro Source

X Yang, B Wang, Q Zhang, A Szekely, M Wu… - …, 2024 - Wiley Online Library
An additive‐free, mild, and regioselective C (1)− H nitration of imidazo [1, 5‐a] pyridine
derivatives was developed. This protocol features the use of easily handled, commercially …

2‐Methoxyethyl Nitrite as a Reagent for Chemoselective On‐Water Nitration

T Kitanosono, A Hashidoko… - Chemistry–An Asian …, 2022 - Wiley Online Library
An on‐water approach has been developed that allows a nitration of tyrosines and phenols
under mild conditions. We envisioned that the assembly of tyrosine/tyrosyl radical couples …

Study on the reaction selectivity and hazard of m-xylene nitration catalyzed by SO3H-functionalized ionic liquids with different anions: Experimental and theoretical …

H Yao, J Huang, Y Ni, Z Cheng, G Fu, L Ni… - Journal of Molecular …, 2024 - Elsevier
Five imidazole based SO 3 H-functionalized ionic liquids (SFILs) with different anions were
selected as catalysts to achieve efficient m-xylene nitration. The acidity and thermal stability …

Hydroxylation of Aryl Sulfonium Salts for Phenol Synthesis under Mild Reaction Conditions

XB Hu, QQ Fu, XY Huang, XQ Chu, ZL Shen, C Miao… - Molecules, 2024 - mdpi.com
Hydroxylation of aryl sulfonium salts could be realized by utilizing acetohydroxamic acid and
oxime as hydroxylative agents in the presence of cesium carbonate as a base, leading to a …