[HTML][HTML] Hyper/neuroinflammation in COVID-19 and suicide etiopathogenesis: Hypothesis for a nefarious collision?

A Costanza, A Amerio, A Aguglia, G Serafini… - Neuroscience & …, 2022 - Elsevier
Accumulating scientific and clinical evidence highlighted pathological hyperinflammation as
a cardinal feature of SARS-CoV-2 infection and acute COVID-19 disease. With the …

NOX2 activation in COVID-19: Possible implications for neurodegenerative diseases

C Sindona, G Schepici, V Contestabile, P Bramanti… - Medicina, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a rapidly spreading contagious infectious disease
caused by the pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

SARS-CoV-2 spike protein disrupts blood–brain barrier integrity via RhoA activation

BJ DeOre, KA Tran, AM Andrews, SH Ramirez… - Journal of Neuroimmune …, 2021 - Springer
The SARS-CoV-2 spike protein has been shown to disrupt blood–brain barrier (BBB)
function, but its pathogenic mechanism of action is unknown. Whether angiotensin …

Optimal serum ferritin level range: Iron status measure and inflammatory biomarker

RG DePalma, VW Hayes, TJ O'Leary - Metallomics, 2021 - academic.oup.com
This report provides perspectives concerning dual roles of serum ferritin as a measure of
both iron status and inflammation. We suggest benefits of a lower range of serum ferritin as …

New insight in the cross-talk between microglia and schizophrenia: From the perspective of neurodevelopment

J Li, Y Wang, X Yuan, Y Kang, X Song - Frontiers in Psychiatry, 2023 - frontiersin.org
Characterized by psychotic symptoms, negative symptoms and cognitive deficits,
schizophrenia had a catastrophic effect on patients and their families. Multifaceted reliable …

Alzheimer's disease and infectious agents: a comprehensive review of pathogenic mechanisms and microRNA roles

SSM Hosseininasab, R Ebrahimi… - Frontiers in …, 2025 - frontiersin.org
Alzheimer's Disease (AD) is the most prevalent type of dementia and is characterized by the
presence of senile plaques and neurofibrillary tangles. There are various theories …

Predicted Environmental Risk Assessment of Antimicrobials with Increased Consumption in Portugal during the COVID-19 Pandemic; The Groundwork for the …

A Almeida, C De Mello-Sampayo, A Lopes… - Antibiotics, 2023 - mdpi.com
The environmental release of antimicrobial pharmaceuticals is an imminent threat due to
ecological impacts and microbial resistance phenomena. The recent COVID-19 outbreak …

Effects of early adjunctive pharmacotherapy on serum levels of brain injury biomarkers in patients with traumatic brain injury: a systematic review of randomized …

NO Mansour, MH Elnaem, DH Abdelaziz… - Frontiers in …, 2023 - frontiersin.org
Objectives: Traumatic brain injury (TBI) is one of the top causes of morbidity and mortality
worldwide. The review aimed to discuss and summarize the current evidence on the …

Neuropathological analysis of the brains of fifty-two patients with COVID-19

T Wierzba-Bobrowicz, P Krajewski, S Tarka… - Folia …, 2021 - termedia.pl
Abstract Coronavirus disease 2019 (COVID-19) poses a global challenge to healthcare and
society in the early 21st century. We report neuropathological changes in 52 patients aged …

Neuroimmune multi-hit perspective of coronaviral infection

S Hayley, H Sun - Journal of Neuroinflammation, 2021 - Springer
It is well accepted that environmental stressors experienced over a one's life, from microbial
infections to chemical toxicants to even psychological stressors, ultimately shape central …