Traditional and novel electrocardiographic conduction and repolarization markers of sudden cardiac death
Sudden cardiac death, frequently due to ventricular arrhythmias, is a significant problem
globally. Most affected individuals do not arrive at hospital in time for medical treatment …
globally. Most affected individuals do not arrive at hospital in time for medical treatment …
Reactive oxygen species, endoplasmic reticulum stress and mitochondrial dysfunction: the link with cardiac arrhythmogenesis
Background: Cardiac arrhythmias represent a significant problem globally, leading to
cerebrovascular accidents, myocardial infarction, and sudden cardiac death. There is …
cerebrovascular accidents, myocardial infarction, and sudden cardiac death. There is …
Intercalated disk nanoscale structure regulates cardiac conduction
The intercalated disk (ID) is a specialized subcellular region that provides electrical and
mechanical connections between myocytes in the heart. The ID has a clearly defined …
mechanical connections between myocytes in the heart. The ID has a clearly defined …
[HTML][HTML] Electrophysiological mechanisms of long and short QT syndromes
The QT interval on the human electrocardiogram is normally in the order of 450 ms, and
reflects the summated durations of action potential (AP) depolarization and repolarization of …
reflects the summated durations of action potential (AP) depolarization and repolarization of …
[HTML][HTML] Conduction abnormalities and ventricular arrhythmogenesis: The roles of sodium channels and gap junctions
G Tse, JM Yeo - IJC Heart & Vasculature, 2015 - Elsevier
Ventricular arrhythmias arise from disruptions in the normal orderly sequence of electrical
activation and recovery of the heart. They can be categorized into disorders affecting …
activation and recovery of the heart. They can be categorized into disorders affecting …
What is the arrhythmic substrate in viral myocarditis? Insights from clinical and animal studies
Sudden cardiac death (SCD) remains an unsolved problem in the twenty-first century. It is
often due to rapid onset, ventricular arrhythmias caused by a number of different clinical …
often due to rapid onset, ventricular arrhythmias caused by a number of different clinical …
Distribution of cardiac sodium channels in clusters potentiates ephaptic interactions in the intercalated disc
E Hichri, H Abriel, JP Kucera - The Journal of physiology, 2018 - Wiley Online Library
Key points It has been proposed that ephaptic conduction, relying on interactions between
the sodium (Na+) current and the extracellular potential in intercalated discs, might …
the sodium (Na+) current and the extracellular potential in intercalated discs, might …
[HTML][HTML] Cardiac disease and arrhythmogenesis: Mechanistic insights from mouse models
The mouse is the second mammalian species, after the human, in which substantial amount
of the genomic information has been analyzed. With advances in transgenic technology …
of the genomic information has been analyzed. With advances in transgenic technology …
The conduction velocity-potassium relationship in the heart is modulated by sodium and calcium
DR King, M Entz, GA Blair, I Crandell… - … -European Journal of …, 2021 - Springer
The relationship between cardiac conduction velocity (CV) and extracellular potassium (K+)
is biphasic, with modest hyperkalemia increasing CV and severe hyperkalemia slowing CV …
is biphasic, with modest hyperkalemia increasing CV and severe hyperkalemia slowing CV …
Reevaluating methods reporting practices to improve reproducibility: an analysis of methodological rigor for the Langendorff whole heart technique
In recent decades, the scientific community has seen an increased interest in rigor and
reproducibility. In 2017, concerns about methodological thoroughness and reporting …
reproducibility. In 2017, concerns about methodological thoroughness and reporting …