Nanozymes, nanomaterial-based artificial enzymes, exhibit potential for emulating the
catalytic functions inherent in enzymes. Nanozymes have advantages such as low cost …

Prodrugs have emerged as a major strategy for addressing clinical challenges by improving
drug pharmacokinetics, reducing toxicity, and enhancing treatment efficacy. The emergence …

High‐entropy alloys nanoparticles (HEANPs) are receiving extensive attention due to their
broad compositional tunability and unlimited potential in bioapplication. However …

Bioorthogonal chemistry provides a new avenue for disease treatment by generating
therapeutic agents in situ. However, two crucial issues have to be considered for future …

Personalized tumor vaccines have become a promising modality for cancer immunotherapy.
However, in situ personalized tumor vaccines generated from immunogenic cancer cell …

Immunotherapy harnesses the inherent immune system in the body to generate systemic
antitumor immunity, offering a promising modality for defending against cancer. However …

Bioorthogonal reactions provide a powerful tool to manipulate biological processes in their
native environment. However, the transition-metal catalysts (TMCs) for bioorthogonal …

Bioorthogonal chemistry is a promising toolbox for dissecting biological processes in the
native environment. Recently, bioorthogonal reactions have attracted considerable attention …

Active polymetallic atomic clusters can initiate heterogeneous catalytic reactions in the tumor
microenvironment, and the products tend to cause manifold damage to cell metabolic …

Cuproptosis, a kind of newly recognized cell death modality, shows enormous prospect in
cancer treatment. The inducer of cuproptosis has more advantages in tumor therapy …