Aptamers for SARS‐CoV‐2: Isolation, characterization, and diagnostic and therapeutic developments

R Amini, Z Zhang, J Li, J Gu, JD Brennan… - Analysis & …, 2022 - Wiley Online Library
The SARS‐CoV‐2 virus and COVID‐19 pandemic continue to demand effective diagnostic
and therapeutic solutions. Finding these solutions requires highly functional molecular …

Clinical performance of rapid antigen tests in comparison to RT‐PCR for SARS‐COV‐2 diagnosis in Omicron variant: A systematic review and meta‐analysis

ZE Mohammadie, S Akhlaghi… - Reviews in Medical …, 2023 - Wiley Online Library
The Omicron variant of concern has a high level of mutations in different genes that has
raised awareness about the performance of immunological products such as vaccines and …

Performance of antigen lateral flow devices in the UK during the alpha, delta, and omicron waves of the SARS-CoV-2 pandemic: a diagnostic and observational study

DW Eyre, M Futschik, S Tunkel, J Wei… - The Lancet Infectious …, 2023 - thelancet.com
Background Antigen lateral flow devices (LFDs) have been widely used to control SARS-
CoV-2. We aimed to improve understanding of LFD performance with changes in variant …

A universal DNA aptamer that recognizes spike proteins of diverse SARS‐CoV‐2 variants of concern

Z Zhang, J Li, J Gu, R Amini, HD Stacey… - … A European Journal, 2022 - Wiley Online Library
We report on a unique DNA aptamer, denoted MSA52, that displays universally high affinity
for the spike proteins of wildtype SARS‐CoV‐2 as well as the Alpha, Beta, Gamma, Epsilon …

Antibody-and aptamer-free SERS substrate for ultrasensitive and anti-interference detection of SARS-CoV-2 spike protein in untreated saliva

H Zhang, C Zhang, Z Wang, W Cao, M Yu… - Biosensors and …, 2023 - Elsevier
Sensitive and anti-interference detection of targeted signal (s) in body fluids is one of the
paramount tasks in biosensing. Overcoming the complication and high cost of …

Evaluation of the diagnostic performance of a SARS-CoV-2 and influenza A/B combo rapid antigen test in respiratory samples

HÖ Dinç, N Karabulut, S Alaçam, HK Uysal… - Diagnostics, 2023 - mdpi.com
This study aimed to evaluate the performance characteristics of a rapid antigen test
developed to detect SARS-CoV-2 (COVID-19), influenza A virus (IAV), and influenza B virus …

[HTML][HTML] Evaluation of multiplex rapid antigen tests for the simultaneous detection of SARS-CoV-2 and influenza A/B viruses

HJ Lim, JY Lee, YH Baek, MY Park, DJ Youm, I Kim… - Biomedicines, 2023 - mdpi.com
Single-target rapid antigen tests (RATs) are commonly used to detect highly transmissible
respiratory viruses (RVs), such as severe acute respiratory syndrome coronavirus 2 (SARS …

High rates of rapid antigen test positivity after 5 days of isolation for COVID-19

E Landon, AH Bartlett, R Marrs, C Guenette, SG Weber… - MedRxiv, 2022 - medrxiv.org
Background The emergence of the highly transmissible COVID-19 variant, omicron, has
resulted in high numbers of breakthrough infections, including among healthcare workers …

[HTML][HTML] Rapid antigen testing for SARS-CoV-2 by lateral flow assay: A field evaluation of self-and professional testing at UK community testing sites

ME Futschik, S Johnson, E Turek, D Chapman… - Journal of Clinical …, 2024 - Elsevier
Background The advent of lateral flow devices (LFDs) for SARS-CoV-2 detection enabled
widespread use of rapid self-tests during the pandemic. While self-testing using LFDs is now …

Test accuracy of rapid diagnostic tests and reverse‐transcription polymerase chain reaction against virus isolation in cell culture for assessing SARS‐CoV‐2 infectivity …

A Fomenko, T Dähne, S Weibel… - Reviews in Medical …, 2024 - Wiley Online Library
We aimed to assess the performance of Ag‐RDT and RT‐qPCR with regard to detecting
infectious SARS‐CoV‐2 in cell cultures, as their diagnostic test accuracy (DTA) compared to …