Most promising approaches to improve stroke outcomes: the stroke treatment academic industry roundtable XII workshop

LR Wechsler, O Adeoye, F Alemseged… - Stroke, 2023 - ahajournals.org
The Stroke Treatment Academic Industry Roundtable XII included a workshop to discuss the
most promising approaches to improve outcome from acute stroke. The workshop brought …

Risk factors, pathophysiologic mechanisms, and potential treatment strategies of futile recanalization after endovascular therapy in acute ischemic stroke

G Deng, Y Chu, J **ao, K Shang, LQ Zhou… - Aging and …, 2023 - pmc.ncbi.nlm.nih.gov
Endovascular therapy is the first-line treatment for acute ischemic stroke. However, studies
have shown that, even with the timely opening of occluded blood vessels, nearly half of all …

No‐reflow after stroke reperfusion therapy: An emerging phenomenon to be explored

M Jia, F **, S Li, C Ren, M Ruchi… - CNS neuroscience & …, 2024 - Wiley Online Library
In the field of stroke thrombectomy, ineffective clinical and angiographic reperfusion after
successful recanalization has drawn attention. Partial or complete microcirculatory …

A promising frontier: targeting NETs for stroke treatment breakthroughs

H Fang, Y Bo, Z Hao, G Mang, J **, H Wang - Cell Communication and …, 2024 - Springer
Stroke is a prevalent global acute cerebrovascular condition, with ischaemic stroke being
the most frequently occurring type. After a stroke, neutrophils accumulate in the brain and …

Incidence, severity and impact on functional outcome of persistent hypoperfusion despite large-vessel recanalization, a potential marker of impaired microvascular …

A Schiphorst, G Turc, WB Hassen… - Journal of Cerebral …, 2024 - journals.sagepub.com
The reported incidence of persistent hypoperfusion despite complete recanalization as
surrogate for impaired microvascular reperfusion (IMR) has varied widely among clinical …

Impacts of futile reperfusion and reperfusion injury in acute ischemic stroke

A Elmadhoun, H Wang, Y Ding - Brain Circulation, 2024 - journals.lww.com
Acute ischemic stroke (AIS) remains to be a challenging cerebrovascular disease. The
mainstay of AIS management is endovascular reperfusion therapy, including thrombectomy …

Blood pressure variability in acute stroke: a narrative review

C Zompola, L Palaiodimou, K Voumvourakis… - Journal of Clinical …, 2024 - mdpi.com
The management of blood pressure variability (BPV) in acute stroke presents a complex
challenge with profound implications for patient outcomes. This narrative review examines …

Normobaric hyperoxia combined with endovascular treatment based on temporal gradient: a dose-escalation study

W Li, S Wang, L Liu, J Chen, J Lan, J Ding, Z Chen… - Stroke, 2024 - ahajournals.org
BACKGROUND: Normobaric hyperoxia (NBO) has neuroprotective effects in acute ischemic
stroke. Thus, we aimed to identify the optimal NBO treatment duration combined with …

[HTML][HTML] A comprehensive prediction model for futile recanalization in ais patients post-endovascular therapy: Integrating clinical, imaging, and no-reflow biomarkers

S Huang, J Xu, H Kang, W Guo, C Ren… - Aging and …, 2024 - pmc.ncbi.nlm.nih.gov
Our study aimed to construct a predictive model for identifying instances of futile
recanalization in patients with anterior circulation occlusion acute ischemic stroke (AIS) who …

Stress hyperglycemia as a modifiable predictor of futile recanalization in patients undergoing mechanical thrombectomy for acute ischemic stroke

G Merlino, S Pez, R Sartor, F Kuris, Y Tereshko… - Frontiers in …, 2023 - frontiersin.org
Introduction Mechanical thrombectomy (MT) is the first line treatment in acute ischemic
stroke (AIS) due to large vessel occlusion (LVO). Approximately half of patients treated with …