Human african trypanosomiasis

P Büscher, G Cecchi, V Jamonneau, G Priotto - The Lancet, 2017 - thelancet.com
Human African trypanosomiasis (slee** sickness) is a parasitic infection that almost
invariably progresses to death unless treated. Human African trypanosomiasis caused …

Epidemiology of human African trypanosomiasis

JR Franco, PP Simarro, A Diarra… - Clinical epidemiology, 2014 - Taylor & Francis
Human African trypanosomiasis (HAT), or slee** sickness, is caused by Trypanosoma
brucei gambiense, which is a chronic form of the disease present in western and central …

The elimination of human African trypanosomiasis: Achievements in relation to WHO road map targets for 2020

JR Franco, G Cecchi, M Paone, A Diarra… - PLoS neglected …, 2022 - journals.plos.org
Background In the 20th century, epidemics of human African trypanosomiasis (HAT)
ravaged communities in a number of African countries. The latest surge in disease …

The pathogenesis of African trypanosomiasis

E Pays, M Radwanska, S Magez - Annual Review of Pathology …, 2023 - annualreviews.org
African trypanosomes are bloodstream protozoan parasites that infect mammals including
humans, where they cause slee** sickness. Long-lasting infection is required to favor …

The skin is a significant but overlooked anatomical reservoir for vector-borne African trypanosomes

P Capewell, C Cren-Travaillé, F Marchesi, P Johnston… - Elife, 2016 - elifesciences.org
The role of mammalian skin in harbouring and transmitting arthropod-borne protozoan
parasites has been overlooked for decades as these pathogens have been regarded …

The elimination of human African trypanosomiasis: Monitoring progress towards the 2021–2030 WHO road map targets

JR Franco, G Priotto, M Paone, G Cecchi… - PLOS Neglected …, 2024 - journals.plos.org
Background Human African trypanosomiasis (HAT) is a neglected tropical disease that
usually occurs in rural areas in sub-Saharan Africa. It caused devastating epidemics during …

Clinical features, diagnosis, and treatment of human African trypanosomiasis (slee** sickness)

PGE Kennedy - The Lancet Neurology, 2013 - thelancet.com
Human African trypanosomiasis, or slee** sickness, is caused by infection with parasites
of the genus Trypanosoma, transmitted by the tsetse fly. The disease has two forms …

Monitoring the elimination of human African trypanosomiasis: Update to 2014

JR Franco, G Cecchi, G Priotto, M Paone… - PLoS neglected …, 2017 - journals.plos.org
Background The World Health Organization (WHO) has targeted the elimination of Human
African trypanosomiasis (HAT)'as a public health problem'by 2020. The selected indicators …

Clinical and neuropathogenetic aspects of human African trypanosomiasis

PGE Kennedy, J Rodgers - Frontiers in immunology, 2019 - frontiersin.org
Trypanosomiasis has been recognized as a scourge in sub-Saharan Africa for centuries.
The disease, caused by protozoan parasites of the Trypanosoma genus, is a major cause of …

Motility and more: the flagellum of Trypanosoma brucei

G Langousis, KL Hill - Nature Reviews Microbiology, 2014 - nature.com
Trypanosoma brucei is a pathogenic unicellular eukaryote that infects humans and other
mammals in sub-Saharan Africa. A central feature of trypanosome biology is the single …