Chitosan (CS) is a hemi-synthetic cationic linear polysaccharide produced by the
deacetylation of chitin. CS is non-toxic, highly biocompatible, and biodegradable, and it has …

Despite the wide range of diseases affecting the eye, ocular bioavailability remains a
challenge in ophthalmic drug delivery. Nowadays an extensive variety of polymers are being …

Glaucoma is a degenerative optic neuropathy characterized by increased intraocular
pressure that if untreated can result in blindness. Ophthalmological drug therapy is a …

Background To date, the rapid clearance from ocular surface has been a huge obstacle for
using eye drops to treat glaucoma, since it has led to the short preocular residence time and …

Glaucoma is the second leading cause of blindness worldwide. Even though significant
advances have been made in its management, currently available antiglaucoma therapies …

Barriers to effective medical therapy are numerous and include difficulties with effective and
sustained control of intraocular pressure (IOP) and adherence to prescribed anti‐glaucoma …

Objective: Glaucoma is a leading cause of irreversible blindness worldwide. Whereas
latanoprost is one of the most effective drugs in glaucoma treatment, its eye drops need …

Prolonged drug efficacy to reduce the number of administrations is a key factor in the
successful treatment of glaucoma through topical drug delivery to the eye. Therefore, we …

The purpose of the present study was to develop and assess a novel sustained-release drug
delivery system of Bimatoprost (BIM). Chitosan polymeric inserts were prepared using the …

Elevation of the intraocular pressure (IOP) is recognized as a risk factor for glaucoma
development. Latanoprost (LAT) is a prostaglandin analog used to reduce the (IOP) …