Fear generalization and anxiety: behavioral and neural mechanisms
Fear can be an adaptive emotion that helps defend against potential danger. Classical
conditioning models elegantly describe how animals learn which stimuli in the environment …
conditioning models elegantly describe how animals learn which stimuli in the environment …
Fear generalization in humans: systematic review and implications for anxiety disorder research
Fear generalization, in which conditioned fear responses generalize or spread to related
stimuli, is a defining feature of anxiety disorders. The behavioral consequences of …
stimuli, is a defining feature of anxiety disorders. The behavioral consequences of …
Overanxious and underslept
Are you feeling anxious? Did you sleep poorly last night? Sleep disruption is a recognized
feature of all anxiety disorders. Here, we investigate the basic brain mechanisms underlying …
feature of all anxiety disorders. Here, we investigate the basic brain mechanisms underlying …
Mechanisms linking childhood adversity with psychopathology: Learning as an intervention target
Exposure to childhood adversity is common and a powerful risk factor for many forms of
psychopathology. In this opinion piece, we argue for greater translation of knowledge about …
psychopathology. In this opinion piece, we argue for greater translation of knowledge about …
Neuroinflammation-associated alterations of the brain as potential neural biomarkers in anxiety disorders
E Won, YK Kim - International journal of molecular sciences, 2020 - mdpi.com
Stress-induced changes in the immune system, which lead to neuroinflammation and
consequent brain alterations, have been suggested as possible neurobiological substrates …
consequent brain alterations, have been suggested as possible neurobiological substrates …
Biological markers of generalized anxiety disorder
E Maron, D Nutt - Dialogues in clinical neuroscience, 2017 - Taylor & Francis
Generalized anxiety disorder (GAD) is a prevalent and highly disabling mental health
condition; however, there is still much to learn with regard to pertinent biomarkers, as well as …
condition; however, there is still much to learn with regard to pertinent biomarkers, as well as …
Influence of reward motivation on human declarative memory
Motivational relevance can prioritize information for memory encoding and consolidation
based on reward value. In this review, we pinpoint the possible psychological and neural …
based on reward value. In this review, we pinpoint the possible psychological and neural …
Fear learning circuitry is biased toward generalization of fear associations in posttraumatic stress disorder
Fear conditioning is an established model for investigating posttraumatic stress disorder
(PTSD). However, symptom triggers may vaguely resemble the initial traumatic event …
(PTSD). However, symptom triggers may vaguely resemble the initial traumatic event …
[HTML][HTML] Systematic review and meta-analyses of neural structural and functional differences in generalized anxiety disorder and healthy controls using magnetic …
TA Kolesar, E Bilevicius, AD Wilson, J Kornelsen - NeuroImage: Clinical, 2019 - Elsevier
Objective To compare structure, functional connectivity (FC) and task-based neural
differences in subjects with generalized anxiety disorder (GAD) compared to healthy …
differences in subjects with generalized anxiety disorder (GAD) compared to healthy …
Fear one, fear them all: A systematic review and meta-analysis of fear generalization in pathological anxiety
L Fraunfelter, ABM Gerdes, GW Alpers - Neuroscience & Biobehavioral …, 2022 - Elsevier
It is a defining feature of anxiety disorders that fear is elicited by a circumscribed class of
stimuli rather than by only one specific exemplar of that class. Therefore, fear generalization …
stimuli rather than by only one specific exemplar of that class. Therefore, fear generalization …