Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …

Ultrasmall nanoparticulate materials with core sizes in the 1-3 nm range bridge the gap
between single molecules and classical, larger-sized nanomaterials, not only in terms of …

Interest in the use of radionuclides for treatment of various diseases has a long history and
parallels the isolation of radium by Marie and Pierre Curie in the early part of the 20th …

The nucleus is an essential organelle for the function of cells. It holds most of the genetic
material and plays a crucial role in the regulation of cell growth and proliferation. Since …

Unique characteristics, such as nontoxicity and rapid cellular internalization, allow the cell-
penetrating peptides (CPPs) to transport hydrophilic macromolecules into cells, thus …

Technetium‐99m (99mTc) is a widely used radionuclide, and the development of 99mTc
imaging agents continues to be in demand. This overview discusses basic principles of …

Abstract Cell-penetrating peptides (CPPs), also known as protein transduction domains, are
a class of diverse peptides with 5‑30 amino acids. CPPs are divided into cationic …

Over the last few decades, gold nanoparticles (GNPs) have emerged as “radiosensitizers” in
oncology. Radiosensitizers are additives that can enhance the effects of radiation on …

Recent advances in the field of nanotechnology applications in nuclear medicine offer the
promise of better diagnostic and therapeutic options. In recent years, increasing efforts have …

Improvements in the treatment of locally advanced breast cancer (LABC) are needed. Our
objective was to study a radiation nanomedicine (gold nanoseeds) composed of 30-nm gold …