Microfluidic production of mRNA-loaded lipid nanoparticles for vaccine applications

C Lopes, J Cristóvão, V Silvério, PR Lino… - Expert opinion on drug …, 2022 - Taylor & Francis
Introduction During past years, lipid nanoparticles (LNPs) have emerged as promising
carriers for RNA delivery, with several clinical trials focusing on both infectious diseases and …

Overcoming technological barriers in microfluidics: Leakage testing

V Silverio, S Guha, A Keiser, R Natu… - … in bioengineering and …, 2022 - frontiersin.org
The miniaturization of laboratory procedures for Lab-on-Chip (LoC) devices and translation
to various platforms such as single cell analysis or Organ-on-Chip (OoC) systems are …

TapeTech microfluidic connectors: adhesive tape-enabled solution for organ-on-a-chip system integration

T Ching, ACI van Steen, D Gray-Scherr, JL Teo… - Lab on a Chip, 2025 - pubs.rsc.org
A longstanding challenge in microfluidics has been the efficient delivery of fluids from macro-
scale pum** systems into microfluidic devices, known as the “world-to-chip” problem …

In the flow of molecular miniaturized fungal diagnosis

M Zolotareva, F Cascalheira, C Caneiras… - Trends in …, 2024 - cell.com
The diagnosis of fungal infections presents several challenges and limitations, stemming
from the similarities in symptomatology, diversity of underlying pathogenic species …

The importance of dimensional traceability in microfluidic systems

E Batista, J Alves e Sousa, F Saraiva, A Lopes… - Metrology, 2024 - mdpi.com
Dimensional measurements are fundamental in microfluidic device manufacturing and
performance. The main focus of this study is the measurement of the connection port sizes in …

[HTML][HTML] Investigations on the performance of a newly developed pressure-driven flow controller used in microfluidic applications

O Büker, K Stolt, E Batista, J Sepulveda… - Measurement …, 2024 - Elsevier
This paper gives an overview of investigations with a newly developed pressure-driven flow
controller, which has no mechanical components and can therefore provide pulsation-free …

[HTML][HTML] Development of measurement procedures for volume and flow related quantities in microfluidic devices

E Batista, V Silverio, K Romieu, JA e Sousa… - Measurement …, 2024 - Elsevier
The precise control of fluids within channels is the common feature of the microfluidic
systems, which endows them with innovative applications and makes them widely applied in …