The neuromuscular junction is the chemical synapse between motor neurons and skeletal
muscle fibers. It is designed to reliably convert the action potential from the presynaptic …

Life originated in anoxia, but many organisms came to depend upon oxygen for survival,
independently evolving diverse respiratory systems for acquiring oxygen from the …

Congenital diaphragmatic hernias (CDHs) and structural anomalies of the diaphragm are a
common class of congenital birth defects that are associated with significant morbidity and …

Congenital diaphragmatic hernia (CDH) is a congenital anomaly consisting of a
posterolateral defect in the diaphragm also known as a Bochdalek hernia. It occurs in 1 in …

Skeletal muscle satellite cells (SC s) are adult muscle stem cells responsible for muscle
regeneration after acute or chronic injuries. The lineage progression of quiescent SC toward …

Abstract Congenital Diaphragmatic Hernia (CDH) is defined by the presence of an orifice in
the diaphragm, more often left and posterolateral that permits the herniation of abdominal …

The mammalian diaphragm muscle is essential for respiration, and thus is one of the most
critical skeletal muscles in the human body. Defects in diaphragm development leading to …

In skeletal muscle, brain-derived neurotrophic factor (BDNF) has long been thought to serve
as a retrograde trophic factor for innervating motor neurons throughout their lifespan …

Congenital diaphragmatic hernia (CDH) is a relatively common birth defect associated with
high mortality and morbidity. Although the exact etiology of most cases of CDH remains …

The outcomes of patients diagnosed with congenital diaphragmatic hernia (CDH) have
recently improved. However, mortality and morbidity remain high, and this is primarily …