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Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions
Background In traditional medicine whole plants or mixtures of plants are used rather than
isolated compounds. There is evidence that crude plant extracts often have greater in vitro …
isolated compounds. There is evidence that crude plant extracts often have greater in vitro …
[HTML][HTML] Plant-derived antimalarial agents: new leads and efficient phytomedicines. Part II. Non-alkaloidal natural products
Malaria is still the most destructive and dangerous parasitic infection in many tropical and
subtropical countries. The burden of this disease is getting worse, mainly due to the …
subtropical countries. The burden of this disease is getting worse, mainly due to the …
[HTML][HTML] Screening for natural and derived bio-active compounds in preclinical and clinical studies: One of the frontlines of fighting the coronaviruses pandemic
Abstract Background Starting December 2019, mankind faced an unprecedented enemy,
the COVID-19 virus. The world convened in international efforts, experiences and …
the COVID-19 virus. The world convened in international efforts, experiences and …
In vivo antimalarial activity of the crude leaf extract and solvent fractions of Croton macrostachyus Hocsht. (Euphorbiaceae) against Plasmodium berghei in mice
L Bantie, S Assefa, T Teklehaimanot… - BMC complementary and …, 2014 - Springer
Background The issue of resistance in malarial infection makes development of novel drugs
a necessity. An alternative source for discovering such drugs is natural products. Croton …
a necessity. An alternative source for discovering such drugs is natural products. Croton …
In vitro antiplasmodial effect of ethanolic extracts of traditional medicinal plant Ocimum species against Plasmodium falciparum
SJ Inbaneson, R Sundaram, P Suganthi - Asian Pacific Journal of tropical …, 2012 - Elsevier
OBJECTIVE: To identify the possible antiplasmodial compounds from leaf, stem, root and
flower extracts of Ocimum canum (O. canum), Ocimum sanctum (O. sanctum) and Ocimum …
flower extracts of Ocimum canum (O. canum), Ocimum sanctum (O. sanctum) and Ocimum …
[HTML][HTML] A literature review on traditional herbal medicines for malaria
Malaria is known to cause around 1 million deaths per annum. This life-threatening disease
is mostly prevalent in Africa. Due to the burgeoning problem of drug resistance, it is getting …
is mostly prevalent in Africa. Due to the burgeoning problem of drug resistance, it is getting …
Naphthylisoquinoline alkaloids potential drug leads
Naphthylisoquinolines are a group of structurally diverse secondary metabolites, consisting
of naphthalene and isoquinoline moieties. Naturally occurring naphthylisoquinolines have …
of naphthalene and isoquinoline moieties. Naturally occurring naphthylisoquinolines have …
Efficacy of lapachol on treatment of cutaneous and visceral leishmaniasis
IAC Araújo, RC de Paula, CL Alves, KF Faria… - Experimental …, 2019 - Elsevier
Leishmaniasis is one of the most important neglected diseases worldwide. It is a life-
threatening disease and causes significant morbidity, long-term disability, and early death …
threatening disease and causes significant morbidity, long-term disability, and early death …
[HTML][HTML] Identification of plumbagin and sanguinarine as effective chemotherapeutic agents for treatment of schistosomiasis
SM Zhang, KA Coultas - International Journal for Parasitology: Drugs and …, 2013 - Elsevier
Schistosomiasis, a snail-borne parasitic disease, affects more than 200 million people
worldwide. Currently the treatment of schistosomiasis relies on a single therapy of …
worldwide. Currently the treatment of schistosomiasis relies on a single therapy of …
Antimalarial activity of crude extract and solvent fractions of the leaves of Bersama abyssinica fresen.(Melianthaceae) against Plasmodium berghei infection in Swiss …
AA Alehegn, JS Yesuf, EM Birru - … ‐Based Complementary and …, 2020 - Wiley Online Library
Background. Treatment of malaria has been compromised by the emergence of drug‐
resistant parasites. Consequently, novel agents are urgently needed from different sources …
resistant parasites. Consequently, novel agents are urgently needed from different sources …