[HTML][HTML] Pharmacotherapy of anxiety disorders: current and emerging treatment options

A Garakani, JW Murrough, RC Freire, RP Thom… - Frontiers in …, 2020 - frontiersin.org
Anxiety disorders are the most prevalent psychiatric disorders and a leading cause of
disability. While there continues to be expansive research in posttraumatic stress disorder …

From Pavlov to PTSD: the extinction of conditioned fear in rodents, humans, and anxiety disorders

MB VanElzakker, MK Dahlgren, FC Davis… - Neurobiology of learning …, 2014 - Elsevier
Abstract Nearly 100 years ago, Ivan Pavlov demonstrated that dogs could learn to use a
neutral cue to predict a biologically relevant event: after repeated predictive pairings …

The future of psychopharmacology: a critical appraisal of ongoing phase 2/3 trials, and of some current trends aiming to de‐risk trial programmes of novel agents

CU Correll, M Solmi, S Cortese, M Fava… - World …, 2023 - Wiley Online Library
Despite considerable progress in pharmacotherapy over the past seven decades, many
mental disorders remain insufficiently treated. This situation is in part due to the limited …

Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the treatment of panic disorder, social anxiety disorder and generalised …

G Andrews, C Bell, P Boyce, C Gale… - Australian & New …, 2018 - journals.sagepub.com
Objective: To provide practical clinical guidance for the treatment of adults with panic
disorder, social anxiety disorder and generalised anxiety disorder in Australia and New …

[HTML][HTML] Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders

N Singewald, C Schmuckermair, N Whittle… - Pharmacology & …, 2015 - Elsevier
Pathological fear and anxiety are highly debilitating and, despite considerable advances in
psychotherapy and pharmacotherapy they remain insufficiently treated in many patients with …

A Randomized, Double-Blind Evaluation of d-Cycloserine or Alprazolam Combined With Virtual Reality Exposure Therapy for Posttraumatic Stress Disorder in Iraq …

BO Rothbaum, M Price, T Jovanovic… - American Journal of …, 2014 - Am Psychiatric Assoc
Objective The authors examined the effectiveness of virtual reality exposure augmented with
d-cycloserine or alprazolam, compared with placebo, in reducing posttraumatic stress …

D-cycloserine augmentation of exposure-based cognitive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders: a systematic review …

D Mataix-Cols, LF De La Cruz, B Monzani… - JAMA …, 2017 - jamanetwork.com
Importance Whether and under which conditions D-cycloserine (DCS) augments the effects
of exposure-based cognitive behavior therapy for anxiety, obsessive-compulsive, and …

Exercise augmentation of exposure therapy for PTSD: rationale and pilot efficacy data

MB Powers, JL Medina, S Burns… - Cognitive behaviour …, 2015 - Taylor & Francis
Brain-derived neurotrophic factor (BDNF) is associated with synaptic plasticity, which is
crucial for long-term learning and memory. Some studies suggest that people suffering from …

Brain connectomics predict response to treatment in social anxiety disorder

S Whitfield-Gabrieli, SS Ghosh, A Nieto-Castanon… - Molecular …, 2016 - nature.com
We asked whether brain connectomics can predict response to treatment for a
neuropsychiatric disorder better than conventional clinical measures. Pre-treatment resting …

Neuroscience of fear extinction: implications for assessment and treatment of fear-based and anxiety related disorders

MR Milad, BL Rosenbaum, NM Simon - Behaviour research and therapy, 2014 - Elsevier
Current exposure-based therapies aimed to reduce pathological fear and anxiety are now
amongst the most effective interventions for trauma and anxiety related disorders …