Current and future perspectives on skin tissue engineering: key features of biomedical research, translational assessment, and clinical application

JR Yu, J Navarro, JC Coburn, B Mahadik… - Advanced …, 2019‏ - Wiley Online Library
The skin is responsible for several important physiological functions and has enormous
clinical significance in wound healing. Tissue engineered substitutes may be used in …

Comprehensive framework for human health risk assessment of nanopesticides

M Kah, LJ Johnston, RS Kookana, W Bruce… - Nature …, 2021‏ - nature.com
Nanopesticides are not only in an advanced state of research and development but have
started to appear on the market. Industry and regulatory agencies need a consolidated and …

Progressive 3D printing technology and its application in medical materials

D Fan, Y Li, X Wang, T Zhu, Q Wang, H Cai… - Frontiers in …, 2020‏ - frontiersin.org
Three-dimensional (3D) printing enables patient-specific anatomical level productions with
high adjustability and resolution in microstructures. With cost-effective manufacturing for …

Novel Methods and Approaches for Safety Evaluation of Nanoparticle Formulations: A Focus Towards In Vitro Models and Adverse Outcome Pathways

MG Tirumala, P Anchi, S Raja, M Rachamalla… - Frontiers in …, 2021‏ - frontiersin.org
Nanotoxicology is an emerging field employed in the assessment of unintentional
hazardous effects produced by nanoparticles (NPs) impacting human health and the …

Nanoengineered silica: Properties, applications and toxicity

AM Mebert, CJ Baglole, MF Desimone… - Food and Chemical …, 2017‏ - Elsevier
Silica nanoparticles are widely used for biomedical purposes, but also in cosmetic products,
food, the car industry, paints, etc. Considering their mega production, one should not ignore …

Genotoxicity testing of nanomaterials

R Landsiedel, N Honarvar, SB Seiffert… - Wiley …, 2022‏ - Wiley Online Library
Nanomaterials have outstanding and unprecedented advantageous material properties but
may also cause adverse effects in humans upon exposure. Testing nanomaterials for …

Comparison of conventional and advanced in vitro models in the toxicity testing of nanoparticles

E Fröhlich - Artificial cells, nanomedicine, and biotechnology, 2018‏ - Taylor & Francis
Humans are exposed to a wide variety of nanoparticles (NPs) present in the environment, in
consumer, health and medical products, and in food. Conventional cytotoxicity testing …

Replacement of animal testing by integrated approaches to testing and assessment (IATA): a call for in vivitrosi

F Caloni, I De Angelis, T Hartung - Archives of Toxicology, 2022‏ - Springer
Alternative methods to animal use in toxicology are evolving with new advanced tools and
multilevel approaches, to answer from one side to 3Rs requirements, and on the other side …

[HTML][HTML] Genotoxicity of nanomaterials: advanced in vitro models and high throughput methods for human hazard assessment—a review

Y Kohl, E Rundén-Pran, E Mariussen, M Hesler… - Nanomaterials, 2020‏ - mdpi.com
Changes in the genetic material can lead to serious human health defects, as mutations in
somatic cells may cause cancer and can contribute to other chronic diseases. Genotoxic …

[HTML][HTML] Skin interaction, permeation, and toxicity of silica nanoparticles: Challenges and recent therapeutic and cosmetic advances

RP Morais, S Hochheim, CC de Oliveira… - International Journal of …, 2022‏ - Elsevier
Silica nanoparticles (SNPs) received more attention with the emergence of nanotechnology
with the aim and promise of becoming innovative drug delivery systems. They have been …