Recent advances in regenerative biomaterials

D Cao, J Ding - Regenerative Biomaterials, 2022 - academic.oup.com
Nowadays, biomaterials have evolved from the inert supports or functional substitutes to the
bioactive materials able to trigger or promote the regenerative potential of tissues. The …

Optimized strategies of ROS-based nanodynamic therapies for tumor theranostics

Y Di, R Deng, Z Liu, Y Mao, Y Gao, Q Zhao, S Wang - Biomaterials, 2023 - Elsevier
Reactive oxygen species (ROS) play a crucial role in regulating the metabolism of tumor
growth, metastasis, death and other biological processes. ROS-based nanodynamic …

In-situ-sprayed therapeutic hydrogel for oxygen-actuated Janus regulation of postsurgical tumor recurrence/metastasis and wound healing

S Chen, Y Luo, Y He, M Li, Y Liu, X Zhou, J Hou… - Nature …, 2024 - nature.com
Surgery is the mainstay of treatment modality for malignant melanoma. However, the
deteriorative hypoxic microenvironment after surgery is recognized as a stemming cause for …

An injectable and active hydrogel induces mutually enhanced mild magnetic hyperthermia and ferroptosis

X Chen, H Wang, J Shi, Z Chen, Y Wang, S Gu, Y Fu… - Biomaterials, 2023 - Elsevier
Magnetic hyperthermia therapy (MHT) is a promising new modality to deal with solid tumors,
yet the low magnetic-heat conversion efficacy, magnetic resonance imaging (MRI) artifacts …

An antibacterial and anti‐oxidative hydrogel dressing for promoting diabetic wound healing and real‐time monitoring wound pH conditions with a NIR fluorescent …

Y Zong, B Zong, R Zha, Y Zhang, X Li… - Advanced …, 2023 - Wiley Online Library
The design and synthesis of multifunctional chitosan hydrogels based on polymerized ionic
liquid and a near‐infrared (NIR) fluorescent probe (PIL‐CS) is a promising strategy, which …

Reactive oxygen species-upregulating nanomedicines towards enhanced cancer therapy

Y Ding, Q Pan, W Gao, Y Pu, K Luo, B He - Biomaterials Science, 2023 - pubs.rsc.org
Reactive oxygen species (ROS) play a crucial role in physiological and pathological
processes, emerging as a therapeutic target in cancer. Owing to the high concentration of …

[HTML][HTML] Sustained co-delivery of 5-fluorouracil and cis-platinum via biodegradable thermo-sensitive hydrogel for intraoperative synergistic combination chemotherapy …

W Chen, K Shi, J Liu, P Yang, R Han, M Pan, L Yuan… - Bioactive materials, 2023 - Elsevier
Gastric cancer is the fifth most common cancer and the third leading cause of cancer death
worldwide, posing a severe threat to human health. Surgical resection remains the most …

Versatile hypoxic extracellular vesicles laden in an injectable and bioactive hydrogel for accelerated bone regeneration

J Deng, X Wang, W Zhang, L Sun, X Han… - Advanced Functional …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) have emerged as
an appealing alternative to cell therapy in regenerative medicine. Unlike bone marrow …

[HTML][HTML] Blending strategy to modify PEEK-based orthopedic implants

Z Chen, Y Chen, J Ding, L Yu - Composites Part B: Engineering, 2023 - Elsevier
Polyetheretherketone (PEEK) is a thermoplastic polymer with strong mechanical properties,
good chemical stability and excellent biocompatibility. Since PEEK was approved as an …

Fibro‐gel: an all‐aqueous hydrogel consisting of microfibers with tunable release profile and its application in wound healing

Y Shen, Y Liu, JK Nunes, C Wang, M Xu… - Advanced …, 2023 - Wiley Online Library
Injectable hydrogels are valuable tools in tissue engineering and regenerative medicine due
to their unique advantages of injectability with minimal invasiveness and usability for …