Global patterns in excess body weight and the associated cancer burden
The prevalence of excess body weight and the associated cancer burden have been rising
over the past several decades globally. Between 1975 and 2016, the prevalence of excess …
over the past several decades globally. Between 1975 and 2016, the prevalence of excess …
Nutrition interventions to treat low muscle mass in cancer
Many patients with cancer experience poor nutritional status, which detrimentally impacts
clinical outcomes. Poor nutritional status in cancer is primarily manifested by severe muscle …
clinical outcomes. Poor nutritional status in cancer is primarily manifested by severe muscle …
Management of cancer cachexia: ASCO guideline
EJ Roeland, K Bohlke, VE Baracos, E Bruera… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To provide evidence-based guidance on the clinical management of cancer
cachexia in adult patients with advanced cancer. METHODS A systematic review of the …
cachexia in adult patients with advanced cancer. METHODS A systematic review of the …
Myosteatosis and prognosis in cancer: systematic review and meta-analysis
Background The evidence that body composition parameters influence multiple cancer
outcomes is rapidly expanding. Excess adiposity deposits in muscle tissue, termed …
outcomes is rapidly expanding. Excess adiposity deposits in muscle tissue, termed …
Updated systematic review and meta-analysis on diagnostic issues and the prognostic impact of myosteatosis: a new paradigm beyond sarcopenia
H Ahn, DW Kim, Y Ko, J Ha, YB Shin, J Lee… - Ageing Research …, 2021 - Elsevier
Myosteatosis, which is excessive fat infiltration in the skeletal muscle, is now considered a
distinct disease from sarcopenia. Advances in imaging technique have made muscle …
distinct disease from sarcopenia. Advances in imaging technique have made muscle …
Body composition and lung cancer-associated cachexia in TRACERx
O Al-Sawaf, J Weiss, M Skrzypski, JM Lam… - Nature medicine, 2023 - nature.com
Cancer-associated cachexia (CAC) is a major contributor to morbidity and mortality in
individuals with non-small cell lung cancer. Key features of CAC include alterations in body …
individuals with non-small cell lung cancer. Key features of CAC include alterations in body …
Population-scale CT-based body composition analysis of a large outpatient population using deep learning to derive age-, sex-, and race-specific reference curves
Background Although CT-based body composition (BC) metrics may inform disease risk and
outcomes, obtaining these metrics has been too resource intensive for large-scale use …
outcomes, obtaining these metrics has been too resource intensive for large-scale use …
Effects of weight loss and sarcopenia on response to chemotherapy, quality of life, and survival
It has frequently been shown that patients with cancer are one of the largest hospital patient
groups with a prevalence for malnutrition. Weight loss is a frequent manifestation of …
groups with a prevalence for malnutrition. Weight loss is a frequent manifestation of …
Reference values for skeletal muscle mass–current concepts and methodological considerations
CO Walowski, W Braun, MJ Maisch, B Jensen, S Peine… - Nutrients, 2020 - mdpi.com
Assessment of a low skeletal muscle mass (SM) is important for diagnosis of ageing and
disease-associated sarcopenia and is hindered by heterogeneous methods and …
disease-associated sarcopenia and is hindered by heterogeneous methods and …
Cancer-cell-secreted miR-122 suppresses O-GlcNAcylation to promote skeletal muscle proteolysis
A decline in skeletal muscle mass and low muscular strength are prognostic factors in
advanced human cancers. Here we found that breast cancer suppressed O-linked N …
advanced human cancers. Here we found that breast cancer suppressed O-linked N …