Modulation of Virulence Factors during Trypanosoma cruzi Differentiation
Chagas disease is a neglected tropical disease caused by Trypanosoma cruzi. This
protozoan developed several mechanisms to infect, propagate, and survive in different …
protozoan developed several mechanisms to infect, propagate, and survive in different …
RNA Binding Proteins and Gene Expression Regulation in Trypanosoma cruzi
The regulation of gene expression in trypanosomatids occurs mainly at the post-
transcriptional level. In the case of Trypanosoma cruzi, the characterization of messenger …
transcriptional level. In the case of Trypanosoma cruzi, the characterization of messenger …
Proteomics uncovers novel components of an interactive protein network supporting RNA export in trypanosomes
AH Inoue, PF Domingues, M Serpeloni… - Molecular & Cellular …, 2022 - ASBMB
In trypanosomatids, transcription is polycistronic and all mRNAs are processed by trans-
splicing, with export mediated by noncanonical mechanisms. Although mRNA export is …
splicing, with export mediated by noncanonical mechanisms. Although mRNA export is …
Trypanosoma cruzi eIF4E3- and eIF4E4-containing complexes bind different mRNAs and may sequester inactive mRNAs during nutritional stress
BP Gabiatti, ER Freire, J Ferreira da Costa… - Nucleic Acids …, 2025 - academic.oup.com
Many eIF4F and poly (A)-binding protein (PABP) paralogues are found in trypanosomes: six
eIF4E, five eIF4G, one eIF4A and two PABPs. They are expressed simultaneously and …
eIF4E, five eIF4G, one eIF4A and two PABPs. They are expressed simultaneously and …
GCN2-Like Kinase Modulates Stress Granule Formation During Nutritional Stress in Trypanosoma cruzi
AM Malvezzi, M Aricó, N Souza-Melo… - Frontiers in cellular …, 2020 - frontiersin.org
The integrated stress response in eukaryotic cells is an orchestrated pathway that leads to
eukaryotic Initiation Factor 2 alpha subunit (eIF2α) phosphorylation at ser51 and ultimately …
eukaryotic Initiation Factor 2 alpha subunit (eIF2α) phosphorylation at ser51 and ultimately …
[HTML][HTML] Identification of the interactomes associated with SCD6 and RBP42 proteins in Leishmania braziliensis
Leishmania are protozoan parasites responsible for leishmaniasis. These parasites present
a precise gene regulation that allows them to survive different environmental conditions …
a precise gene regulation that allows them to survive different environmental conditions …
Characterization of the RNA-Binding Protein TcSgn1 in Trypanosoma cruzi
RNA-binding proteins (RBPs) participate in several steps of post-transcriptional regulation of
gene expression, such as splicing, messenger RNA transport, mRNA localization, and …
gene expression, such as splicing, messenger RNA transport, mRNA localization, and …
Formation of mRNP granules in Toxoplasma gondii during the lytic cycle
S Roscoe, E Manni, M Roberts… - Molecular and biochemical …, 2021 - Elsevier
Two poly (A) binding proteins (PABPs) of Toxoplasma gondii, were identified and
characterized. They were named TgPABPC and TgPABPN as they were found to localize in …
characterized. They were named TgPABPC and TgPABPN as they were found to localize in …
Two distinct Trypanosoma eIF4F complexes co-exist, bind different mRNAs and are regulated during nutritional stress
BP Gabiatti, ER Freire, JF da Costa, MG Ferrarini… - bioRxiv, 2024 - biorxiv.org
Many eIF4F subunits and PABP paralogues are found in trypanosomes: six eIF4E, five
eIF4G, one eIF4A and two PABPs. They are expressed simultaneously and assemble into …
eIF4G, one eIF4A and two PABPs. They are expressed simultaneously and assemble into …
[PDF][PDF] Characterization of the RNA-Binding Protein TcSgn1 in Trypanosoma cruzi. Microorganisms 2021, 9, 986
C Oliveira, AP Gerber, S Goldenberg, LR Alves - 2021 - academia.edu
RNA-binding proteins (RBPs) participate in several steps of post-transcriptional regulation of
gene expression, such as splicing, messenger RNA transport, mRNA localization, and …
gene expression, such as splicing, messenger RNA transport, mRNA localization, and …