[HTML][HTML] Repurposing therapeutic drugs complexed to vanadium in cancer

AL De Sousa-Coelho, G Fraqueza, M Aureliano - Pharmaceuticals, 2023 - mdpi.com
Repurposing drugs by uncovering new indications for approved drugs accelerates the
process of establishing new treatments and reduces the high costs of drug discovery and …

The role of zinc to mitigate heavy metals toxicity in crops

MU Hassan, M Nawaz, A Mahmood… - Frontiers in …, 2022 - frontiersin.org
Heavy metal (HM) contamination is a serious concern across the globe, and in recent times,
HMs' intensity has significantly increased, posing a serious threat to crop growth and …

Metformin: a narrative review of its potential benefits for cardiovascular disease, cancer and dementia

WMC Top, A Kooy, CDA Stehouwer - Pharmaceuticals, 2022 - mdpi.com
The biguanide metformin has been used as first-line therapy in type 2 diabetes mellitus
(T2DM) treatment for several decades. In addition to its glucose-lowering properties and its …

[HTML][HTML] Metformin prevents or delays the development and progression of osteoarthritis: new insight and mechanism of action

M He, B Lu, M Opoku, L Zhang, W **e, H **, S Chen… - Cells, 2022 - mdpi.com
For over 60 years, metformin has been widely prescribed by physicians to treat type 2
diabetes. Along with more in-depth research on metformin and its molecular mechanism in …

[HTML][HTML] Biological properties of transition metal complexes with metformin and its analogues

DA Rusanov, J Zou, MV Babak - Pharmaceuticals, 2022 - mdpi.com
Metformin is a widely prescribed medication for the treatment and management of type 2
diabetes. It belongs to a class of biguanides, which are characterized by a wide range of …

Copper nanoparticles encapsulated in reduced graphene oxide electrode (CuxrGO1-x) for the electrochemical quantification of metformin in water

YJ Shih, YQ Su, WH Chen, SK Lin, YC He… - Chemical Engineering …, 2023 - Elsevier
Electrochemical oxidation of anti-diabetic metformin (MTF) drug was studied on glassy
carbon electrode (GCE) prepared by electroplating of copper nanoparticles (Cu NPs) on …

[HTML][HTML] Fabrication and characterization of CuO nano-needles from thermal decomposition of Cu (II) metal complex: Fluorometric detection of antibiotics, antioxidant …

V Sumalatha, D Ayodhya - Results in Chemistry, 2023 - Elsevier
In the present study, CuO NPs and CuO nano-needles were synthesized using thermal
decomposition of Cu (II) complex derived from 2-(4-(trifluoromethoxy) phenylimino) methyl) …

Facile synthesis of a glutathione-depleting Cu (II)-half-salamo-based coordination polymer for enhanced chemodynamic therapy

W Guo, T Ji, Y Deng, J Liu, Y Gou, W Dong - Dalton Transactions, 2022 - pubs.rsc.org
Chemodynamic therapy (CDT), utilizing Fenton catalysts to convert intracellular H2O2 into
toxic hydroxyl radicals (˙ OH) to kill cancer cells, has a wide application prospect in tumor …

Metals and metal-nanoparticles in human pathologies: from exposure to therapy

JI Lachowicz, LI Lecca, F Meloni, M Campagna - Molecules, 2021 - mdpi.com
An increasing number of pathologies correlates with both toxic and essential metal ions
dyshomeostasis. Next to known genetic disorders (eg, Wilson's Disease and β-Thalassemia) …