From the clinical standpoint, systemic sclerosis (SSc) is characterized by skin and internal
organ fibrosis, diffuse fibroproliferative vascular modifications, and autoimmunity. Clinical …

Objective Immune checkpoint inhibitors (ICI s) are improving prognoses in advanced stage
cancers, but they also lead to immune‐related adverse events (IRAE s). IRAE s targeting …

Disease-specific autoantibodies are considered the most important biomarkers for systemic
sclerosis (SSc), due to their ability to stratify patients with different severity and prognosis …

Systemic sclerosis is a complex autoimmune disease characterized by a chronic and
frequently progressive course and by extensive patient-to-patient variability. Like other …

Systemic sclerosis, also called scleroderma, is an immune-mediated rheumatic disease that
is characterised by fibrosis of the skin and internal organs and vasculopathy. Although …

Autoimmune diseases are thought to be initiated by exposures to foreign antigens that cross-
react with endogenous molecules. Scleroderma is an autoimmune connective tissue …

Connective tissue diseases (CTDs) such as systemic lupus erythematosus, systemic
sclerosis, myositis, Sjögren's syndrome, and rheumatoid arthritis are systemic diseases …

Systemic sclerosis is an autoimmune disease characterized by fibrosis of skin and internal
organs, vasculopathy, and dysregulation of immune system. A diagnostically important …

Purpose of review The association between autoimmunity and cancer is well established.
Cancer has been implicated in some autoimmune disorders (AID), such as scleroderma and …

Background Data on survival and prognosis factors in incident cohorts are scarce in
systemic sclerosis (SStc). To describe survival, standardized mortality ratio (SMR), and …