Addiction is driven by excessive goal-directed drug choice under negative affect: translational critique of habit and compulsion theory

L Hogarth - Neuropsychopharmacology, 2020 - nature.com
Drug addiction may be a goal-directed choice driven by excessive drug value in negative
affective states, a habit driven by strong stimulus− response associations, or a compulsion …

Beyond dichotomies in reinforcement learning

AGE Collins, J Cockburn - Nature Reviews Neuroscience, 2020 - nature.com
Reinforcement learning (RL) is a framework of particular importance to psychology,
neuroscience and machine learning. Interactions between these fields, as promoted through …

Computational psychiatry needs time and context

PF Hitchcock, EI Fried, MJ Frank - Annual review of psychology, 2022 - annualreviews.org
Why has computational psychiatry yet to influence routine clinical practice? One reason may
be that it has neglected context and temporal dynamics in the models of certain mental …

Advances in the computational understanding of mental illness

QJM Huys, M Browning, MP Paulus… - …, 2021 - nature.com
Computational psychiatry is a rapidly growing field attempting to translate advances in
computational neuroscience and machine learning into improved outcomes for patients …

[HTML][HTML] Identifying transdiagnostic mechanisms in mental health using computational factor modeling

T Wise, OJ Robinson, CM Gillan - Biological Psychiatry, 2023 - Elsevier
Most psychiatric disorders do not occur in isolation, and most psychiatric symptom
dimensions are not uniquely expressed within a single diagnostic category. Current …

Improving the reliability of computational analyses: Model-based planning and its relationship with compulsivity

VM Brown, J Chen, CM Gillan, RB Price - Biological Psychiatry: Cognitive …, 2020 - Elsevier
Background Computational models show great promise in map** latent decision-making
processes onto dissociable neural substrates and clinical phenotypes. One prominent …

Computational models of subjective feelings in psychiatry

CH Kao, GW Feng, JK Hur, H Jarvis… - … & Biobehavioral Reviews, 2023 - Elsevier
Research in computational psychiatry is dominated by models of behavior. Subjective
experience during behavioral tasks is not well understood, even though it should be relevant …

Determining the effects of training duration on the behavioral expression of habitual control in humans: A multilaboratory investigation

ER Pool, R Gera, A Fransen, OD Perez… - Learning & …, 2022 - learnmem.cshlp.org
It has been suggested that there are two distinct and parallel mechanisms for controlling
instrumental behavior in mammals: goal-directed actions and habits. To gain an …

Associations between aversive learning processes and transdiagnostic psychiatric symptoms in a general population sample

T Wise, RJ Dolan - Nature communications, 2020 - nature.com
Symptom expression in psychiatric conditions is often linked to altered threat perception,
however how computational mechanisms that support aversive learning relate to specific …

Transdiagnostic phenoty** reveals a host of metacognitive deficits implicated in compulsivity

TXF Seow, CM Gillan - Scientific reports, 2020 - nature.com
Recent work suggests that obsessive-compulsive disorder (OCD) patients have a
breakdown in the relationship between explicit beliefs (ie confidence about states) and …