Simple Summary The cytoskeleton is a network of protein fibres within cells that provide
structure and support intracellular transport. Focal adhesions are protein complexes …

The involvement of complement in the regulation of antibody responses has been known for
long. By now several additional B cell functions–including cytokine production and antigen …

Podosomes are a distinctive form of integrin-mediated cellmatrix adhesion typical of
monocyte-derived cells but under some circumstances produced by cells of other lineages …

Extensive in vitro studies have described podosomes as actin-based structures at the
plasma membrane, connecting the cell with its extracellular matrix and endowed with …

Podosomes are mechanosensitive attachment/invasion structures that form on the matrix-
adhesion interface of cells and protrude into the extracellular matrix to probe and remodel …

Platelet concentrates are produced in order to treat bleeding disorders. They can be
provided by apheresis machines or by pooling of buffy coats from four blood donations …

Bone resorption by osteoclasts is mediated by a typical adhesion structure called the sealing
zone or actin ring, whose architecture is based on a belt of podosomes. The molecular …

Fibroblasts transformed by the proto-oncogene Src form individual invadopodia that can
spontaneously self-organize into large matrix-degrading superstructures called rosettes …

Invadosomes are actin-based protrusions formed by cells in response to obstacles in their
microenvironment, especially basement membranes and dense interstitial matrices. A …

Osteoclasts (OCs) can adhere to a variety of substrate surfaces by highly dynamic actin‐
based cytoskeletal structures termed podosomes. This tight attachment is established by a …