Immune checkpoint therapy (ICT) has dramatically altered clinical outcomes for cancer
patients and conferred durable clinical benefits, including cure in a subset of patients …

High rates of failure, exorbitant costs, and the sluggish pace of new drug discovery and
development have led to a growing interest in repurposing “old” drugs to treat both common …

CD8+ T cells are essential components of the immune response against viral infections and
tumours, and are capable of eliminating infected and cancerous cells. However, when the …

Tumor‐associated macrophages (TAMs) play an essential role in tumor progression,
metastasis, and antitumor immunity. Ferroptosis has attracted extensive attention for its …

The physiological consequences of stress often manifest in the gastrointestinal tract.
Traumatic or chronic stress is associated with widespread maladaptive changes throughout …

Recent advancements in understanding the tumor microenvironment (TME) have
highlighted the critical role of the nervous system in cancer progression. This review …

Simple Summary Hemangiosarcoma is a mesenchymal neoplasm that originates in the
endothelial cells of blood vessels. According to the location of origin, they can be classified …

Immunotherapy has revolutionized the treatment of dozens of cancers and became a
standard of care for some tumor types. However, the majority of patients do not benefit from …

Facing cancer diagnosis, patients with cancer are prone to psychological stress and
consequent psychological disorders. The association between psychological stress and …

Background Pancreatic ductal adenocarcinoma (PDAC) is associated with very poor
survival, making it the third and fourth leading cause of all cancer-related deaths in the USA …